Martina Samiotaki Research Group

2024

Krithara A, Nentidis A, Vandorou E, Katsimpras G, Almirantis Y, Arnal M, Bunevicius A, Farre-Maduell E, Kassiss M, Konstantakos V, Matis-Mitchell S, Polychronopoulos D, Rodriguez-Pascual J, Samaras EG, Samiotaki M, Sanoudou D, Vozi A, Paliouras G. 2024, "BioASQ Synergy: A Dialogue between QA systems and biomedical experts for promoting COVID-19 research", J Am Med Inform Assoc., 2024 Aug 24: ocae232. doi: 10.1093/jamia/ocae232. Online ahead of print. [PubMed].

Stefanakis K, Samiotaki M, Papaevangelou V, Valenzuela-Vallejo L, Giannoukakis N, Mantzoros CS. 2024, "Longitudinal proteomics of leptin treatment in humans with acute and chronic energy deficiency-induced hypoleptinemia reveal novel, mainly immune-related, pleiotropic effects.", Metabolism., 2024 Oct; 159:155984. doi: 10.1016/j.metabol.2024.155984. Epub 2024 Aug 2. [PubMed].

Angelopoulou E, Kitani R.-A, Stroggilos R, Lygirou V, Vasilakis I.-A, Letsou K, Vlahou A, Zoidakis J, Samiotaki M, Kanaka-Gantenbein, C. et al. 2024, "Tear Proteomics in Children and Adolescents with Type 1 Diabetes: A Promising Approach to Biomarker Identification of Diabetes Pathogenesis and Complications", Int. J. Mol. Sci. 2024, 25, 9994. [doi].

Theodoros Rampias, Thomas Antoniou, Annelies Stevaert, Lara Kravariti, Benjamin Van Loy, Julie Vandeput, Jacopo Sgrignani, Natalia Filippidou, Patrizia Locatelli, Samiotaki M, Eleftherios Paraskevas Tzakos, Andrea Cavalli, Lieve Naesens, Diamantis C. Sideris, Andreas G. Tzakos. 2024, "Exploration of isatin-based inhibitors of SARS-CoV-2 Nsp15 endoribonuclease", European Journal of Medicinal Chemistry, 2024, 116886, ISSN 0223-5234, [doi].

Chrysanthi Polychroniadou, Michail Michailidis, Martina Samiotaki, Ioannis-Dimosthenis S. Adamakis, Eleni Giannoutsou, Christina Skodra, Evangelos Karagiannis, Christos Bazakos, Athanassios Molassiotis, Georgia Tanou. 2024, "Understanding the effect of calcium in kiwifruit ripening and establishment of early and late response mechanisms through a cross-omics approach.", Postharvest Biology and Technology, 211, 112803 [Link].

G Bakratsas, Samiotaki M, P Katapodis, H Stamatis. 2024, "Proteomic Analysis of Pleurotus ostreatus Grown on Glucose and Xylose Mixtures in Submerged Fermentation Provides Insights into Differentiated Mycelial Composition", Synthetic Biology and Engineering, 2 - 1 10006 [Link].

Armakolas A, Alevizopoulos N, Stathaki M, Petraki C, Agrogiannis G, Samiotaki M, Panayotou G, Chatzinikita E, Koutsilieris M. 2024, "Anti-PEc: Development of a novel monoclonal antibody against prostate cancer.", Br J Cancer., 2024 Jun 20. doi: 10.1038/s41416-024-02713-8. Online ahead of print. [PubMed].

Varveri A, Papadopoulou M, Papadovasilakis Z, Compeer EB, Legaki AI, Delis A, Damaskou V, Boon L, Papadogiorgaki S, Samiotaki M, Foukas PG, Eliopoulos AG, Hatzioannou A, Alissafi T, Dustin ML, Verginis P. 2024, "Immunological synapse formation between T regulatory cells and cancer-associated fibroblasts promotes tumour development.", Nat Commun., 2024 Jun 11; 15(1):4988. doi: 10.1038/s41467-024-49282-1. [PubMed].

Papakonstantinou E, Dragoumani K, Mataragka A, Bacopoulou F, Yapijakis C, Balatsos NA, Pissaridi K, Ladikos D, Eftymiadou A, Katsaros G, Gikas E, Hatzis P, Samiotaki M, Aivaliotis M, Megalooikonomou V, Giannakakis A, Iliopoulos C, Bongcam-Rudloff E, Kossida S, Eliopoulos E, Chrousos GP, Vlachakis D. 2024, "Fingerprinting Breast Milk; insights into Milk Exosomics.", EMBnet J., 2024;29:e1048. doi: 10.14806/ej.29.0.1048. Epub 2024 May 22. [PubMed].

Karakosta C, Samiotaki M, Panayotou G, Papaconstantinou DS, Moschos MM. 2024, "Lens Cytoskeleton: An Update on the Etiopathogenesis of Human Cataracts.", Cureus., 2024 Mar 23; 16(3):e56793. doi: 10.7759/cureus.56793. eCollection 2024 Mar. [PubMed].

Papadopoulou D, Mavrikaki V, Charalampous F, Tzaferis C, Samiotaki M, Papavasileiou KD, Afantitis A, Karagianni N, Denis MC, Sanchez J, Lane JR, Faidon Brotzakis Z, Skretas G, Georgiadis D, Matralis AN, Kollias G. 2024, "Discovery of the First-in-Class Inhibitors of Hypoxia Up-Regulated Protein 1 (HYOU1) Suppressing Pathogenic Fibroblast Activation.", Angew Chem Int Ed Engl., 2024 Apr 2; 63(14):e202319157. doi: 10.1002/anie.202319157. Epub 2024 Feb 26. [PubMed].

Chrysanthi Polychroniadou, Michail Michailidis, Samiotaki M, Ioannis-Dimosthenis S Adamakis, Eleni Giannoutsou, Christina Skodra, Evangelos Karagiannis, Christos Bazakos, Athanassios Molassiotis, Georgia Tanou. 2024, "Understanding the effect of calcium in kiwifruit ripening and establishment of early and late response mechanisms through a cross-omics approach.", Postharvest Biology and Technology, 211 112803 [Link].

Arseni C, Samiotaki M, Panayotou G, Simos G, Mylonis I. 2024, "Combinatorial regulation by ERK1/2 and CK1δ protein kinases leads to HIF-1α association with microtubules and facilitates its symmetrical distribution during mitosis.", Cell Mol Life Sci., 2024 Feb 1; 81(1):72. doi: 10.1007/s00018-024-05120-7. [PubMed].

Samiotaki M, Panayotou G, Chandris P. 2024, "Detection of Protein Tyrosine Phosphatase Interacting Partners by Mass Spectrometry.", Methods Mol Biol., 2024;2743:165-180. doi: 10.1007/978-1-0716-3569-8_11. 2743:165-180. doi: 10.1007/978-1-0716-3569-8_11. [PubMed].

2023

Lefa P, Samiotaki M, Farmaki T. 2023, "Proteome Analysis of the ROF-FKBP Mutants Reveals Functional Relations among Heat Stress Responses, Plant Development, and Protein Quality Control during Heat Acclimation in Arabidopsis thaliana. ", ACS Omega., 2023 Dec 26; 9(2):2391-2408. doi: 10.1021/acsomega.3c06773 [PubMed].

Megarioti AH, Esch BM, Athanasopoulos A, Koulouris D, Makridakis M, Lygirou V, Samiotaki M, Zoidakis J, Sophianopoulou V, André B, Fröhlich F, Gournas C. 2023, "Ferroptosis-protective membrane domains in quiescence.", Cell Rep., 2023 Dec 26; 42(12):113561. doi: 10.1016/j.celrep.2023.113561. Epub 2023 Dec 12. [PubMed].

Goutakoli P, Papadaki G, Repa A, Avgoustidis N, Kalogiannaki E, Flouri I, Bertsias A, Zoidakis J, Samiotaki M, Bertsias G, Semitekolou M, Verginis P, Sidiropoulos P. 2023, "A Peripheral Blood Signature of Increased Th1 and Myeloid Cells Combined with Serum Inflammatory Mediators Is Associated with Response to Abatacept in Rheumatoid Arthritis Patients.", Cells., 2023 Dec 9; 12(24):2808. doi: 10.3390/cells12242808. [PubMed].

Karousi P, Samiotaki M, Makridakis M, Zoidakis J, Sideris DC, Scorilas A, Carell T, Kontos CK. 2023, "3'-tRF-Cys^GCA overexpression in HEK-293 cells alters the global expression profile and modulates cellular processes and pathways.", Funct Integr Genomics., 2023 Nov 21; 23(4):341. doi: 10.1007/s10142-023-01272-0. [PubMed].

Bekas N, Samiotaki M, Papathanasiou M, Mokos P, Pseftogas A, Xanthopoulos K, Thanos D, Mosialos G, Dafou D. 2023, "Inactivation of Tumor Suppressor CYLD Inhibits Fibroblast Reprogramming to Pluripotency.", Cancers (Basel)., 2023 Oct 15; 15(20):4997. doi: 10.3390/cancers15204997. [PubMed].

Stanojevic A, Samiotaki M, Lygirou V, Marinkovic M, Nikolic V, Stojanovic- Rundic S, Jankovic R, Vlahou A, Panayotou G, Fijneman RJA, Castellví-Bel S, Zoidakis J, Cavic M. 2023, "Data-Independent Acquisition Mass Spectrometry Analysis of FFPE Rectal Cancer Samples Offers In-Depth Proteomics Characterization of the Response to Neoadjuvant Chemoradiotherapy.", Int J Mol Sci., 2023 Oct 21, 24(20):15412. doi: 10.3390/ijms242015412 [PubMed].

Georgiou X, Dimou S, Diallinas G, Samiotaki M. 2023, "The interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking.", Fungal Genet Biol., 2023 Sep 18; 169:103840. doi: 10.1016/j.fgb.2023.103840. Epub ahead of print. [PubMed].

Stergioti EM, Manolakou T, Sentis G, Samiotaki M, Kapsala N, Fanouriakis A, Boumpas DT, Banos A. 2023, "Transcriptomic and proteomic profiling reveals distinct pathogenic features of peripheral non-classical monocytes in systemic lupus erythematosus. ", Clin Immunol., 2023 Oct; 255:109765. doi: 10.1016/j.clim.2023.109765. Epub 2023 Sep 9. [PubMed].

Papadaki V, Erpapazoglou Z, Kokkori M, Rogalska ME, Potiri M, Birladeanu A, Tsakiri EN, Ashktorab H, Smoot DT, Papanikolopoulou K, Samiotaki M, Kafasla P. 2023, "IQGAP1 mediates the communication between the nucleus and the mitochondria via NDUFS4 alternative splicing.", NAR Cancer., 2023 Aug 24; 5(3):zcad046. doi: 10.1093/narcan/zcad046. [PubMed].

Melachroinou K, Divolis G, Tsafaras G, Karampetsou M, Fortis S, Stratoulias Y, Papadopoulou G, Kriebardis AG, Samiotaki M, Vekrellis K. 2023, "Endogenous Alpha- Synuclein is Essential for the Transfer of Pathology by Exosome-Enriched Extracellular Vesicles, Following Inoculation with Preformed Fibrils in vivo. ", Aging Dis. , 2023 Aug 4. doi: 10.14336/AD.2023.0614. Epub ahead of print. [PubMed].

Begolli R, Chatziangelou M, Samiotaki M, Goutas A, Barda S, Goutzourelas N, Kevrekidis DP, Malea P, Trachana V, Liu M, Lin X, Kollatos N, Stagos D, Giakountis A. 2023, "Transcriptome and proteome analysis reveals the anti-cancer properties of Hypnea musciformis marine macroalga extract in liver and intestinal cancer cells.", Hum Genomics. , 2023 Jul 31; 17(1):71. doi: 10.1186/s40246-023-00517-0. [PubMed].

Pantazopoulou M, Lamprokostopoulou A, Karampela DS, Alexaki A, Delis A, Coens A, Samiotaki M, Kriebardis AG, Melki R, Pagakis SN, Stefanis L, Vekrellis K. 2023, "Differential intracellular trafficking of extracellular vesicles in microglia and astrocytes. ", Cell Mol Life Sci., 2023 Jun 30; 80(7):193. doi: 10.1007/s00018-023-04841-5. [PubMed].

Temponeras I, Samiotaki M, Koumantou D, Nikopaschou M, Kuiper JJW, Panayotou G, Stratikos E. 2023, "Distinct modulation of cellular immunopeptidome by the allosteric regulatory site of ER aminopeptidase 1.", Eur J Immunol., 2023 May 3: e2350449. doi: 10.1002/eji.202350449. Online ahead of print. [PubMed].

Papadopoulos G, Legaki AI, Georgila K, Vorkas P, Giannousi E, Stamatakis G, Moustakas II, Petrocheilou M, Pyrina I, Gercken B, Kassi E, Chavakis T, Pateras IS, Panayotou G, Gika H, Samiotaki M, Eliopoulos AG, Chatzigeorgiou A. 2023, "Integrated omics analysis for characterization of the contribution of high fructose corn syrup to non-alcoholic fatty liver disease in obesity. ", Metabolism., 2023 Jul; 144:155552. doi: 10.1016/j.metabol.2023.155552. Epub 2023 Mar 28. [PubMed].

Katsiougiannis S, Stergiopoulos A, Moustaka K, Havaki S, Samiotaki M, Stamatakis G, Tenta R, Skopouli FN. 2023, "Salivary gland epithelial cell in Sjögren's syndrome: Metabolic shift and altered mitochondrial morphology toward an innate immune cell function. ", J Autoimmun. , 2023 Apr ;136:103014. doi: 10.1016/j.jaut.2023.103014. Epub 2023 Mar 8. [PubMed].

Gomes PA, Bodo C, Nogueras-Ortiz C, Samiotaki M, Chen M, Soares-Cunha C, Silva JM, Coimbra B, Stamatakis G, Santos L, Panayotou G, Tzouanou F, Waites CL, Gatsogiannis C, Sousa N, Kapogiannis D, Costa-Silva B, Sotiropoulos I. 2023, "A novel isolation method for spontaneously released extracellular vesicles from brain tissue and its implications for stress-driven brain pathology. ", Cell Commun Signal., 2023 Feb 13; 21(1):35. doi: 10.1186/s12964-023-01045-z. [PubMed].

Stylianaki EA, Magkrioti C, Ladopoulou EM, Papavasileiou KD, Lagarias P, Melagraki G, Samiotaki M, Panayotou G, Dedos SG, Afantitis A, Aidinis V, Matralis AN. 2023, ""Hit" to lead optimization and chemoinformatic studies for a new series of Autotaxin inhibitors.", Eur J Med Chem., 2023 Mar 5; 249:115130. doi: 10.1016/j.ejmech.2023.115130. Epub 2023 Jan 23. [PubMed].

Boutsika A, Michailidis M, Ganopoulou M, Dalakouras A, Skodra C, Xanthopoulou A, Stamatakis G, Samiotaki M, Tanou G, Moysiadis T, Angelis L, Bazakos C, Molassiotis A, Nianiou-Obeidat I, Mellidou I, Ganopoulos I. 2023, "A wide foodomics approach coupled with metagenomics elucidates the environmental signature of potatoes.", iScience., 2023 Jan 5; 26(1):105917. doi: 10.1016/j.isci.2022.105917. eCollection 2023 Jan 20. [PubMed].

Skodra C, Michailidis M, Moysiadis T, Stamatakis G, Ganopoulou M, Adamakis IS, Angelis L, Ganopoulos I, Tanou G, Samiotaki M, Bazakos C, Molassiotis A. 2023, "Disclosing the molecular basis of salinity priming in olive trees using proteogenomic model discovery.", Plant Physiol., 2023 Mar 17; 191(3):1913-1933. doi: 10.1093/plphys/kiac572. [PubMed].

2022

• Skodra C, Michailidis M, Moysiadis T, Stamatakis G, Ganopoulou M, Adamakis IS, Angelis L, Ganopoulos I, Tanou G, Samiotaki M, Bazakos C, Molassiotis A. "Disclosing the molecular basis of salinity priming in olive trees using proteogenomic model discovery." Plant Physiol. 2022 Dec 12:kiac572. doi: 10.1093/plphys/kiac572. Online ahead of print. PMID: 36508356

• Taze C, Drakouli S, Samiotaki M, Panayotou G, Simos G, Georgatsou E, Mylonis I. "Short-term hypoxia triggers ROS and SAFB mediated nuclear matrix and mRNA splicing remodeling." Redox Biol. 2022 Dec;58:102545. doi: 10.1016/j.redox.2022.102545. Epub 2022 Nov 17. PMID: 36427398

• Manolakou T, Nikolopoulos D, Gkikas D, Filia A, Samiotaki M, Stamatakis G, Fanouriakis A, Politis P, Banos A, Alissafi T, Verginis P, Boumpas DT. "ATR-mediated DNA damage responses underlie aberrant B cell activity in systemic lupus erythematosus." Sci Adv. 2022 Oct 28;8(43):eabo5840. doi: 10.1126/sciadv.abo5840. Epub 2022 Oct 28. PMID: 36306362

• Georgiou-Siafis SK, Samiotaki M, Demopoulos VJ, Panayotou G, Tsiftsoglou AS. "Glutathione-Hemin/Hematin Adduct Formation to Disintegrate Cytotoxic Oxidant Hemin/Hematin in Human K562 Cells and Red Blood Cells' Hemolysates: Impact of Glutathione on the Hemolytic Disorders and Homeostasis." Antioxidants (Basel). 2022 Sep 30;11(10):1959. doi: 10.3390/antiox11101959. PMID: 36290682

• Armakolas A, Dimopoulou V, Nezos A, Stamatakis G, Samiotaki M, Panayotou G, Tampaki M, Stathaki M, Dourakis S, Koskinas J. "Cellular, Molecular and Proteomic Characteristics of Early Hepatocellular Carcinoma." Curr Issues Mol Biol. 2022 Oct 10;44(10):4714-4734. doi: 10.3390/cimb44100322. PMID: 36286037

• Pappa E, Vastardis H, Makridakis M, Zoidakis J, Vougas K, Stamatakis G, Samiotaki M, Rahiotis C. "Analysis of Human and Microbial Salivary Proteomes in Children Offers Insights on the Molecular Pathogenesis of Molar-Incisor Hypomineralization." Biomedicines. 2022 Aug 24;10(9):2061. doi: 10.3390/biomedicines10092061. PMID: 36140166

• Prifti E, Tsakiri EN, Vourkou E, Stamatakis G, Samiotaki M, Skoulakis EMC, Papanikolopoulou K., "Mical modulates Tau toxicity via cysteine oxidation in vivo.", Acta Neuropathol Commun. 2022 Apr 4;10(1):44. doi: 10.1186/s40478-022-01348-1.

• Temponeras I, Stamatakis G, Samiotaki M, Georgiadis D, Pratsinis H, Panayotou G, Stratikos E., "ERAP2 Inhibition Induces Cell-Surface Presentation by MOLT-4 Leukemia Cancer Cells of Many Novel and Potentially Antigenic Peptides.", Int J Mol Sci. 2022 Feb 8;23(3):1913. doi: 10.3390/ijms23031913.

• Antoniou N, Prodromidou K, Kouroupi G, Boumpoureka I, Samiotaki M, Panayotou G, Xilouri M, Kloukina I, Stefanis L, Grailhe R, Taoufik E, Matsas R., "High content screening and proteomic analysis identify a kinase inhibitor that rescues pathological phenotypes in a patient-derived model of Parkinson's disease.", NPJ Parkinsons Dis. 2022 Feb 11;8(1):15. doi: 10.1038/s41531-022-00278-y.

• Perivolidi VI, Violitzi F, Ioannidou E, Rinotas V, Stamatakis G, Samiotaki M, Panayotou G, Douni E., "Proteomic Identification of the SLC25A46 Interactome in Transgenic Mice Expressing SLC25A46-FLAG.", J Proteome Res. 2022 Feb 4;21(2):375-394. doi: 10.1021/acs.jproteome.1c00728. Epub 2022 Jan 5.

• Karra AG, Sioutopoulou A, Gorgogietas V, Samiotaki M, Panayotou G, Psarra AG., "Proteomic analysis of the mitochondrial glucocorticoid receptor interacting proteins reveals pyruvate dehydrogenase and mitochondrial 60 kDa heat shock protein as potent binding partners.", J Proteomics. 2022 Apr 15;257:104509. doi: 10.1016/j.jprot.2022.104509. Epub 2022 Feb 4.

• Katsarou K, Adkar-Purushothama CR, Tassios E, Samiotaki M, Andronis C, Lisón P, Nikolaou C, Perreault JP, Kalantidis K., "Revisiting the Non-Coding Nature of Pospiviroids.", Cells. 2022 Jan 13;11(2):265. doi: 10.3390/cells11020265.

• Xanthopoulou A, Moysiadis T, Bazakos C, Karagiannis E, Karamichali I, Stamatakis G, Samiotaki M, Manioudaki M, Michailidis M, Madesis P, Ganopoulos I, Molassiotis A, Tanou G., "The perennial fruit tree proteogenomics atlas: a spatial map of the sweet cherry proteome and transcriptome.", Plant J. 2022 Mar;109(5):1319-1336. doi: 10.1111/tpj.15612. Epub 2021 Dec 16.

• Tsolaki VC, Georgiou-Siafis SK, Tsamadou AI, Tsiftsoglou SA, Samiotaki M, Panayotou G, Tsiftsoglou AS. "Hemin accumulation and identification of a heme-binding protein clan in K562 cells by proteomic and computational analysis.", J Cell Physiol. 2022 Feb;237(2):1315-1340. doi: 10.1002/jcp.30595. Epub 2021 Oct 7.

2021

• Koukoulas K, Giakountis A, Karagiota A, Samiotaki M, Panayotou G, Simos G, Mylonis I., "ERK signaling controls productive HIF-1 binding to chromatin and cancer cell adaptation to hypoxia through HIF-1α interaction with NPM1.", Mol Oncol. 2021 Dec;15(12):3468-3489. doi: 10.1002/1878-0261.13080. Epub 2021 Sep 9.

• Stamatakis G, Samiotaki M, Temponeras I, Panayotou G, Stratikos E., "Allotypic variation in antigen processing controls antigenic peptide generation from SARS-CoV-2 S1 spike glycoprotein.", J Biol Chem. 2021 Nov;297(5):101329. doi: 10.1016/j.jbc.2021.101329. Epub 2021 Oct 22.

• Miliotou AN, Papagiannopoulou D, Vlachaki E, Samiotaki M, Laspa D, Theodoridou S, Tsiftsoglou AS, Papadopoulou LC., "PTD-mediated delivery of α-globin chain into Κ-562 erythroleukemia cells and α-thalassemic (HBH) patients' RBCs ex vivo in the frame of Protein Replacement Therapy.", J Biol Res (Thessalon). 2021 Jul 20;28(1):16. doi: 10.1186/s40709-021-00148-3.

• Karagiannis E, Michailidis M, Skodra C, Stamatakis G, Dasenaki M, Ganopoulos I, Samiotaki M, Thomaidis NS, Molassiotis A, Tanou G., "Proteo-metabolomic journey across olive drupe development and maturation.", Food Chem. 2021 Nov 30;363:130339. doi: 10.1016/j.foodchem.2021.130339. Epub 2021 Jun 9.

• Theodorakis E, Antonakis AN, Baltsavia I, Pavlopoulos GA, Samiotaki M, Amoutzias GD, Theodosiou T, Acuto O, Efstathiou G, Iliopoulos I., "ProteoSign v2: a faster and evolved user-friendly online tool for statistical analyses of differential proteomics.", Nucleic Acids Res. 2021 Jul 2;49(W1):W573-W577. doi: 10.1093/nar/gkab329.

• Gkotinakou IM, Befani C, Samiotaki M, Panayotou G, Liakos P., "Novel HIF-2α interaction with Reptin52 impairs HIF-2 transcriptional activity and EPO secretion.", Biochem Biophys Res Commun. 2021 Jun 11;557:143-150. doi: 10.1016/j.bbrc.2021.03.176. Epub 2021 Apr 14.

• Testempasis S, Tanou G, Minas I, Samiotaki M, Molassiotis A, Karaoglanidis G., "Unraveling Interactions of the Necrotrophic Fungal Species Botrytis cinerea With 1-Methylcyclopropene or Ozone-Treated Apple Fruit Using Proteomic Analysis.", Front Plant Sci. 2021 Mar 10;12:644255. doi: 10.3389/fpls.2021.644255. eCollection 2021.

• Prifti E, Tsakiri EN, Vourkou E, Stamatakis G, Samiotaki M, Papanikolopoulou K. “The Two Cysteines of Tau Protein Are Functionally Distinct and Contribute Differentially to Its Pathogenicity in Vivo.” J Neurosci. 27;41(4):797-810. 2021.

• George Karaoglanidis, Stefanos Gabriel Testempasis, Georgia Tanou, Ioannis Minas, M. Samiotaki, Athanassios Molassiotis. “Unraveling interactions of the necrotrophic fungal species Botrytis cinerea with 1-MCP or ozone-treated apple fruit using proteomic analysis.” Frontiers in Plant Science, 2021.

• Stefos, Georgios; Szantai, Eszter; Konstantopoulos, Dimitris; Samiotaki, M.; Fousteri, Maria – “aniFOUND: Analysing the associated proteome and genomic landscape of the repaired nascent non-replicative chromatin” NAR-02435-Met-G-2020.R1. 2021.

2020

• Karagiannis, Evangelos; Tanou, Georgia; Scossa, Federico; Samiotaki, M.; Michailidis, Michail; Manioudaki, Maria; Laurens, François; Job, Dominique; Fernie, Alisdair; Orsel, Mathilde; Molassiotis, Athanassios “Systems-based approaches to unravel networks and individual elements involved in apple superficial scald”. Front. Plant Sci. - Plant Abiotic Stress. 2020.

• Sofia K Georgiou-Siafis, M. Samiotaki, Vassilis J Demopoulos, George Panayotou, Asterios Tsiftsoglou. “Formation of novel N-acetylcysteine-hemin adducts abrogates hemin-induced cytotoxicity and suppresses the NRF2-driven stress response in human pro-erythroid K562 cells. Eur J Pharmacol. 5;880:173077. 2020.

• Stamatakis G, Samiotaki M, Mpakali A, Panayotou G, Stratikos E. “Generation of SARS-CoV-2 S1 Spike Glycoprotein Putative Antigenic Epitopes in Vitro by Intracellular Aminopeptidases.” J Proteome Res. 6;19(11):4398-4406. 2020.

• Michailidis M, Karagiannis E, Tanou G, Samiotaki M, Tsiolas G, Sarrou E, Stamatakis G, Ganopoulos I, Martens S, Argiriou A, Molassiotis A. “Novel insights into the calcium action in cherry fruit development revealed by high-throughput mapping.”. Plant Mol Biol. 104(6):597-614. 2020.

• Karagiannis E, Michailidis M, Tanou G, Scossa F, Sarrou E, Stamatakis G, Samiotaki M, Martens S, Fernie AR, Molassiotis A “Decoding altitude-activated regulatory mechanisms occurring during apple peel ripening.” Hortic Res. 1;7:120. 2020.

• Paspaltsis I, Kesidou E, Touloumi O, Lagoudaki R, Boziki M, Samiotaki M, Dafou D, Sklaviadis T, Grigoriadis N. “Application of antibody phage display to identify potential antigenic neural precursor cell proteins.” J Biol Res (Thessalon). 2;27:14. 2020.

• Papavasileiou A, Tanou G, Samaras A, Samiotaki M, Molassiotis A, Karaoglanidis G. “Proteomic analysis upon peach fruit infection with Monilinia fructicola and M. laxa identify responses contributing to brown rot resistance.” Sci Rep. 8;10(1):7807. 2020.

• Michailidis M, Karagiannis E, Tanou G, Samiotaki M, Sarrou E, Karamanoli K, Lazaridou A, Martens S, Molassiotis A. “Proteomic and metabolic analysis reveals novel sweet cherry fruit development regulatory points influenced by girdling.” Plant Physiol Biochem. 149:233-244. 2020.

2019

• Papadaki M, Rinotas V, Violitzi F, Thireou T, Panayotou G, Samiotaki M, Douni E. “New Insights for RANKL as a Proinflammatory Modulator in Modeled Inflammatory Arthritis.” Frontiers in Immunology: 10:97. 2019.

• Marazioti A, Papadia K, Kannavou M, Spella M, Basta A, de Lastic AL, Rodi M, Mouzaki A, Samiotaki M, Panayotou G, Stathopoulos GT, Antimisiaris SG. “Cellular Vesicles: New Insights in Engineering Methods, Interaction with Cells and Potential for Brain Targeting.” J Pharmacol Exp Ther.;370(3):772-785. 2019.

• Daras G, Rigas S, Alatzas A, Samiotaki M, Chatzopoulos D, Tsitsekian D, Papadaki V, Templalexis D, Banilas G, Athanasiadou AM, Kostourou V, Panayotou G, Hatzopoulos P.“LEFKOTHEA Regulates Nuclear and Chloroplast mRNA Splicing in Plants.” Developmental Cell. 12. pii: S1534-5807(19)30630-6. 2019.

• Papanikolopoulou K, Roussou I, Gouzi J, Samiotaki M, Panayotou G, Turin L, and Skoulakis E. “Drosophila Tau negatively regulates translation and olfactory Long-Term Memory, but facilitates footshock habituation and cytoskeletal homeostasis". Journal of Neuroscience. 2019.

• Foteini Violitzi, Vasiliki-Iris Perivolidi, Trias Thireou, Ioannis Grivas, Sylva Haralambous, M. Samiotaki, George Panayotou, Eleni Douni. “Mapping interactome networks of DNAJC11, a novel mitochondrial protein causing neuromuscular pathology in mice”. J Proteome Res. 18(11):3896-3912. 2019.

2018

• Papanikolopoulou K, Grammenoudi S, Samiotaki M, Skoulakis EMC. , "Differential effects of 14-3-3 dimers on Tau phosphorylation, stability and toxicity in vivo". Hum Mol Genet.;27(13): 2244-2261.2018.

• Papadopoulou ES, Perruchon C, Vasileiadis S, Rousidou C, Tanou G, Samiotaki M, Molassiotis A, Karpouzas DG. “Metabolic and Evolutionary Insights in the Transformation of Diphenylamine by a Pseudomonas putida Strain Unravelled by Genomic, Proteomic, and Transcription Analysis.” Frontiers in microbiology. 9:676. 2018.

• Karagiannis E, Michailidis M, Tanou G, Samiotaki M, K Karamanoli K, Avramidou E, Ganopoulos I, Padesis P, Molassiotis A. “Ethylene–dependent and–independent superficial scald resistance mechanisms in ‘Granny Smith’apple fruit”. Scientific reports 8 (1), 11436. 2018.

• Kotsiri M, Protopapa M, Mouratidis S, Zachariadis M, Vassilakos D, Kleidas I, Samiotaki M, Dedos S, “ Should I stay or should I go? The settlement-inducing protein complex guides barnacle settlement decisions”. Journal of Experimental Biology, 185348. 2018.

• L Papadopoulou, A Ingendoh-Tsakmakidis, C Mpoutoureli, L Tzikalou, E Spyridou, G Gavriilidis, G Kaiafas, A Ntaska, E Vlachaki, G Panayotou, M Samiotaki, Asterios S Tsiftsoglou. “Production and Transduction of a Human Recombinant β Globin Chain into Proerythroid K 562 Cells To Replace Missing Endogenous β Globin”. Mol. Pharmaceutics, 15(12):5665-5677. 2018.

• Christodoulou-Vafeiadou E, Ioakeimidis F, Andreadou M, Giagkas G, Stamatakis G, Recsko M, Samiotaki M, Papanastasiou A, Karakasiliotis I and Kontoyiannis D. "Divergent Innate and Epithelial Functions of the RNA-Binding Protein HuR in Intestinal Inflammation". Frontiers in Immunology: 10.3389. 2018.

2017

• Terzenidou M, Segklia A, Kano T, Papastefanaki F, Karakostas A, Charalambous M, Ioakeimidis F, Papadaki M, Kloukina I, Chrysanthou-Piterou M, Samiotaki M, Panayotou G, Matsas R, Douni E. "Novel Insights into SLC25A46-Related Pathologies in a Genetic Mouse Model". PLoS Genet. 13(4):e1006656. doi:10.1371/journal.pgen.1006656. 2017.

• C Perruchon, S Vasileiadis, K Rousidou, E Papadopoulo, G Tanou, M Samiotaki, C Garagounis, A Molassiotis, and K Papadopoulou and D Karpouzas "Metabolic pathway and cell adaptation mechanisms revealed through genomic, proteomic and transcription analysis of a Sphingomonas haloaromaticamans strain degrading ortho-phenylphenol”. Sci Rep. 2017 Jul 25;7(1):6449. doi: 10.1038/s41598-017-06727-6. 2017.

• Chatzileontiadou DSM, Samiotaki M, Alexopoulou AN, Cotsiki M, Panayotou G, Stamatiadi M, Balatsos NAA, Leonidas DD, Kontou M. “Proteomic analysis of human Angiogenin interactions reveals cytoplasmic PCNA as a putative binding partner.” J Proteome Res.2017.

• Karampetsou M, Ardah MT, Semitekolou M, Polissidis A, Samiotaki M, Kalomoiri M, Majbour N, Xanthou G, El-Agnaf OMA, Vekrellis K. “Phosphorylated exogenous alpha-synuclein fibrils exacerbate pathology and induce neuronal dysfunction in mice”. Sci Rep. 7(1):16533. 2017.

2016

• Maria Agallou, Evita Athanasiou, Martina Samiotaki, George Panayotou, Evdokia Karagouni. “Identification of Leishmania infantum immunodominant antigens associated with resistance profile of asymptomatic canine leishmaniasis as candidate vaccine antigens against leishmaniasis.” PLoS One. 11(2):e0149894 2016.

• Aggeliki Ainalidou, Georgia Tanou, Martina Samiotaki, Maya Belghazi, Diamantidis Grigorios, Athanassios Molassiotis, Karamanoli Katerina. “Integrated analysis of metabolites and proteins reveal aspects of the tissue-specific function of synthetic cytokinin in kiwifruit development and ripening.” J Proteomics. 143:318-33. 2016.
• Elkouris M, Kontaki H, Stavropoulos A, Antonoglou A, Nikolaou KC, Samiotaki M, Szantai E, Saviolaki D, Brown PJ, Sideras P, Panayotou G, Talianidis I. “SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis.” Cell Rep. 15(12):2733-44. 2016.

• Moulos P, Samiotaki M, Panayotou G, Dedos SG. “Combinatory annotation of cell membrane receptors and signalling pathways of Bombyx mori prothoracic glands.” Sci Data. 3:160073. 2016.

• Karagiannis E, Tanou G, Samiotaki M, Michailidis M, Diamantidis G, Minas IS, Molassiotis A. “Comparative Physiological and Proteomic Analysis Reveal Distinct Regulation of Peach Skin Quality Traits by Altitude.” Front Plant Sci. 7:1689. 2016.

• Pangou E, Befani C, Mylonis I, Samiotaki M, Panayotou G, Simos G and Liakos P “Hypoxia Inducible Factor 2α phosphorylation by casein kinase 1δ promotes erythropoietin secretion in liver cancer cells under hypoxia.” J Cell Sci. jcs.191395. 2016.

• Mylonis I, Kourti M, Samiotaki M, Panayotou G, and Simos G. “Mortalin-mediated and ERK-dependent targeting of HIF-1&[alpha] to mitochondria confers resistance to apoptosis under hypoxia.” J Cell Sci. pii: jcs.195339. 2016.

• Fouka P, Alexopoulos H, Chatzi I, Dedos S, Samiotaki M, Panayotou G, Politis P, Tzioufas A and Dalakas M.“Antibodies to Inositol 1,4,5-triphosphate receptor 1 in patients with cerebellar disease”. Neurol Neuroimmunol Neuroinflamm. 5;4(1):e306. 2016.

2015-2001

• Zamanou A, Samiotaki M, Panayotou G, Margaritis L. Lymberi P. Fine specificity and subclasses of IgG anti-actin autoantibodies differ in health and disease. Journal of Autoimmunity: 20(4):333-44. 2003.

• M. Vardakou, P. Katapodis, M. Samiotaki, D. Kekos, G. Panayotou, P. Christakopoulos. Mode of action of family 10 and 11 endoxylanases on water-unextractable arabinoxylan. The International Journal of Biological Macromolecules. 33: 129-134. 2003.

• Sidera K, Samiotaki M, Yfanti E, Panayotou G, Patsavoudi E. Involvement of cell surface HSP90 in cell migration reveals a novel role in the developing nervous system. J Biol Chem. 279(44):45379-88. 2004.

• Vynios DH, Tsagaraki I, Grigoreas GH, Samiotaki M, Panayotou G, Kyriakopoulou D, Georgiou P, Korbakis D, Panayotou A, Nanouri K, Assouti M, Andonopoulos AP. Autoantibodies against aggrecan in systemic rheumatic diseases. Biochimie. 88(7):767-73. 2006.

• Mylonis I, Chachami G, Samiotaki M, Panayotou G, Paraskeva E, Kalousi A, Georgatsou E, Bonanou S, Simos G. Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha. J Biol Chem. 281(44):33095-106. 2006.

• Lindtner S, Zolotukhin AS, Uranishi H, Bear J, Kulkarni V, Smulevitch S, Samiotaki M, Panayotou G, Felber BK, Pavlakis GN. RNA-binding Motif Protein 15 Binds to the RNA Transport Element RTE and Provides a Direct Link to the NXF1 Export Pathway. J Biol Chem. 281(48):36915-28. 2006.

• Tsoupras AB, Antonopoulou S, Baltas G, Samiotaki M, Panayotou G, Kotsifaki H, Mantzavinos Z, Demopoulos CA. Isolation and identification of hydroxyl-platelet-activating factor from natural sources. Life Sci. 79(19):1796-803. 2006.

• E. A. Stea, J. G. Routsias , M. Samiotaki, G. Panayotou , E. Papalambros, H. M. Moutsopoulos and A. G. Tzioufas. Analysis of parotid glands of primary Sjögrens syndrome patients using proteomic technology reveals altered autoantigen composition and novel antigenic targets. Clinical & Experimental Immunology, 147, Issue 1. 81-99. 2007.

• Fragopoulou E., Nomikos T., Karantonis C.H., Apostolakis C., Pliakis E., Samiotaki M., Panagyotou G., Antonopoulou S. Biological Activity of Acetylated Phenolic Compounds. J Agric Food Chem. 55(1):80-9. 2007.

• D. Tsimogiannis, M. Samiotaki, G. Panayotou, V. Oreopoulou. Characterization of flavonoid subgroup and hydroxy substitution with HPLC-MS/MS. Molecules: 593-606. 2007

• Karantonis C.H., Tsantila N., Stamatakis G., Samiotaki M., Panayotou G., Antonopoulou S. and Demopoulos CA. Bioactive polar lipids in olive oil, pomace and waste byproducts. Journal of Food Biochemistry, Vol 32, Issue 4, p443-459. 2007.

• Fragopoulou E, Nomikos T, Karantonis HC, Apostolakis C, Pliakis E, Samiotaki M, Panayotou G, Antonopoulou S. Biological activity of acetylated phenolic compounds. J Agric Food Chem. 10;55(1):80-9. 2007.

• Petroutsos D., Katapodis P., Samiotaki M., Panayotou G. & Kekos D. Detoxification of 2,4-dichlorophenol by the marine microalga Tetraselmis marina. Phytochemistry. 69(3):707-14. 2008.

• Koliaraki V, Marinou M, Samiotaki M, Panayotou G, Pantopoulos K, Mamalaki A. Iron regulatory and bactericidal properties of human recombinant hepcidin expressed in Pichia pastoris. Biochimie. 90(5):726-35. 2008.

• Sikara MP, Routsias JG, Samiotaki M, Panayotou G, Moutsopoulos HM, Vlachoyiannopoulos PG. {beta}2 glycoprotein I ({beta}2GPI) binds platelet factor 4 (PF4): implications for the pathogenesis of antiphospholipid syndrome. Blood. 115, 713-723. 2009.

• Stamatakis G, Tsantila N, Samiotaki M, Panayotou GN, Dimopoulos AC, Halvadakis CP, Demopoulos CA. Detection and Isolation of Antiatherogenic and Antioxidant Substances Present in Olive Mill Wastes by a Novel Filtration System. J Agric Food Chem. 2009.

• Ikonomou, G., Samiotaki, M. and Panayotou G. Proteomic approaches in colon cancer research. Crit. Rev. Clin. Lab. Sci.. 46(5-6):319-42. 2009. Review.

• Makridakis M, Roubelakis MG, Bitsika V, Dimuccio V , Samiotaki M, Kossida S, Panayotou G, Coleman J, Candiano G, Anagnou NP, Vlahou A., "Analysis of secreted proteins for the study of bladder cancer cell aggressiveness. ", J Proteome Res. 9(6): 3243-59. 2010.

• Tsangaridou E, Polioudaki H, Sfakianaki R, Samiotaki M, Tzardi M, Koulentaki M, Panayotou G , Kouroumalis E, Castanas E, Theodoropoulos PA. "Differential detection of nuclear envelope autoantibodies in primary biliary cirrhosis using routine and alternative methods", BMC Gastroenterol, 10., 28. 2010.

• Rapti A, Trangas T, Samiotaki M , Ioannidis P, Dimitriadis E, Meristoudis C, Veletza S, Courtis N. "The structure of the 5'-untranslated region of mammalian poly(A) polymerase-alpha mRNA suggests a mechanism of translational regulation .", Mol Cell Biochem. 2010 Jul;340(1-2):91-6. 2010.

• Parapouli M, Fragkos-Livanios L, Samiotaki M, Koukkou A, Perisynakis A, Hatziloukas E, Panayotou G , Drainas C., "Comparative proteomic analysis of alcoholic fermentation employing a new environmental strain of Saccharomyces cerevisiae ." Process Biochemistry. 45: 1094-1102. 2010.

• Cotsiki M, Oehrl W, Samiotaki M, Theodosiou A, Panayotou G. “Phosphorylation of the M3/6 dual-specificity phosphatase enhances the activation of JNK by arsenite.” Cell Signalling. 24(3): 664-76. 2011.

• Chatzovoulos P, Tsoupras AB, Samiotaki M, Panayotou G, Demopoulos C.A., Dotsika A. “PAF-metabolic enzymes and PAF-like activity in L. Infantum and L. Major promastigotes”. European Journal of Inflammation 9 (3): 231-239. 2011.

• Mpakali A, Kotini A, Spella M, Kouyialis M, Tserga A, Fragkos-Livanios L, Samiotaki M, Agalioti T. “p68/Ddx5 RNA helicase interacts and colocalizes in vivo with the de novo DNA methyltransferases Dnmt3a1 and Dnmt3a2.” Journal of Proteomics and Bioinformatics 5(1): 007-014. 2012.

• Irini Evnouchidou, James Birtley, Sergey Seregin, Athanasios Papakyriakou, Thalia Zervoudi, Martina Samiotaki, George Panayotou, Olivia Petrakis, Dimitris Georgiadis, Andrea Amalfitano, Emmanuel Saridakis, Irine Mavridis and Efstratios Stratikos “A common SNP in ER aminopeptidase 2 induces a specificity switch that leads to altered antigen processing”. J Immunol. 189(5):2383-92. 2012.

• Ikonomou G, Vassiliki Kostourou V, Shirasawa S, Sasazuki T, Samiotaki M, Panayotou G. Interplay between oncogenic K-Ras and wild-type H-Ras in Caco2 cell transformation. J Proteomics. 75(17):5356-69. 2012.

• Alexandratos A, Clos J, Samiotaki M, Efstathiou A, Panayotou G, Soteriadou K, Smirlis D. “The loss of virulence of histone H1 overexpressing Leishmania donovani parasites is directly associated with a reduction of HSP83 rate of translation.” Mol Microbiol. 88(5):1015-31. 2013.

• Ioanna Nikitopoulou, Eleanna Kaffe, Ioanna Sevastou, Ivi Sirioti, Martina Samiotaki, Damian Madan, Glenn D Prestwich, Vassilis Aidinis. "A metabolically-stabilized phosphonate analog of lysophosphatidic acid attenuates collagen-induced arthritis". PLoS One 8 (7): e70941. 2013

• Papadopoulou A, Gole E, Moutafi A, Sfikas C, Oehrl W, Samiotaki M, Papadimitriou A, Papaevagelou V, Nicolaidou P. “Calcium sensing receptor in pregnancies complicated by gestational diabetes mellitus.” Placenta. 35(8):632-8. 2014.

• Vandera E, Samiotaki M., Parapouli M., Panayotou G., Koukkou A. "Comparative proteomic analysis of Arthrobacter phenanthrenivorans Sphe3 on phenanthrene, phthalate and glucose." J Proteomics. 113:73-89. 2015.

1993-2001

• Parik J., Kwiatkowski M., Lagerkvist A., Lagerstrom M., Samiotaki M., Stewart J., Glad G., Mendel- Hartvig M, Landegren U. Anal Biochem. Vol. 211, 144-150. 1993.

• Samiotaki M., Kwiatkowski M., Parik J., Landegren U. Dual color detection of DNA sequence variants through ligase-mediated analysis. Genomics, Vol. 20, 238-242. 1994.

• Kwiatkowski M., Samiotaki M., Lamminmaki U., Mukkala V., Landegren U. Solid-phase synthesis of chelate-labelled oligonucleotides: application in triple-color ligase mediated gene analysis. Nucleic Acids Research, Vol. 22, 2604-2611. 1994.

• Nilsson M., Malmgren H., Samiotaki M., Kwiatkowski M., Chowdary B., Landegren U. Padlock probes: Circularizing oligonucleotides for localized DNA detection. Science, Vol. 265. 2085-2088. 1994.

• Landegren U., Samiotaki M., Nilsson M., Malmgren H., Kwiatkowski M. Detecting genes with ligases. Methods: a companion to Methods in Enzymology, 9, 84-90. 1996.

• Samiotaki M, Kwiatkowski M, Ylitalo N, Landegren U. Seven-color time-resolved fluorescence hybridization analysis of human papilloma virus types. Analytical Biochemistry, Vol. 253(2):156-61.1997.

• Hagberg A, Barbany G, Krook H, Samiotaki M, Landegren U. Expression profiling across many samples via manifold-assisted mRNA processing.
Nucleic Acids Res. 1;28(11):E54. 2000.

• Samiotaki M, Balatsos NA, Courtis N, Tsiapalis CM. Assignment of the 100-kDa subunit of cleavage and polyadenylation specificity factor (CPSF2) to human chromosome 14q31.3 by radiation hybrid mapping. Cytogenet Cell Genet. 90(3-4):328-9. 2000.

• Samiotaki M, Balatsos NA, Courtis N, Tsiapalis CM. Assignment of the 160-kDa subunit of cleavage and polyadenylation specificity factor (CPSF1) to human chromosome 8q24.23 by radiation hybrid mapping. Cytogenet Cell Genet. 90(3-4):234-5. 2000.

• Ioannidis P, Trangas T, Dimitriadis E, Samiotaki M, Kyriazoglou I, Tsiapalis CM, Kittas C, Agnantis N, Nielsen FC, Nielsen J, Christiansen J, Pandis N. C-MYC and IGF-II mRNA-binding protein (CRD-BP/IMP-1) in benign and malignant mesenchymal tumors. Int J Cancer. Nov15; 94(4):480-4. 2001.