Proteomics

The BSRC “Alexander Fleming” Proteomics Facility offers services for the quantitative analysis of proteins and the characterization of their interactions and post-translational modifications.

Committed to staying at the forefront of proteomics research, our facility has recently acquired state of-the-art mass spectrometry equipment, single-cell isolation instrumentation and advanced data analysis software through the EU-funded Recovery & Resilience Fund.

These technological advancements enable us to identify and quantify proteins with unprecedented precision and sensitivity, ensuring high-quality data generation for diverse research projects.

Cutting-edge Instrumentation

Providing outstanding tools for advanced proteomics, our current instrumentation is comprised of three mass spectrometers, a newly acquired state-of-the-art timsTOF Ultra 2 (Bruker) coupled to the nanoElute 2 UPLC system (Bruker), an impact II VIP QTOF (Bruker T-ReX LC-QTOF solution) and a Q Exactive HF-X hybrid quadrupole-Orbitrap coupled to an UltiMate 3000 RSLCnano System (Thermo Scientific).

In addition, we have also recently expanded our Proteomics Facility with the acquisition of the cellenONE X1 Neo single-cell isolation platform (Cellenion), adding futher analytical capabilities to our proteomic workflows.

Proteomic Analysis Software

• ProteoScape (including the Spectronaut and DIA-NN module)
• GlycoScape
• MetaboScape
• Proteome Discoverer 2.4
• MaxQuant
• MSFragger
• DIA-NN
• Skyline

Infrastructures and Collaborations

The Proteomics Facility is a key participant in the National Research Infrastructure for Personalised Medicine (pMedGR), as well as the InfrafrontierGR/Phenotypos infrastructure and provides access to all academic users.

Doing a proteomics experiment with us

If you are interested in doing a proteomics project with us, please read our General Guidelines and fill out and submit the General Request Form first. We will then contact you with further information on how to proceed with sample submission.

Contact Information