Panagiota Kafasla Research Group

Papadaki V, Erpapazoglou Z, Kokkori M, Rogalska ME, Potiri M, Birladeanu A, Tsakiri EN, Ashktorab H, Smoot DT, Papanikolopoulou K, Samiotaki M, Kafasla P. 2023, "IQGAP1 mediates the communication between the nucleus and the mitochondria via NDUFS4 alternative splicing", NAR Cancer., 2023 Aug 24; 5(3):zcad046. [PubMed], [DOI].

Rogalska ME, Vafiadaki E, Erpapazoglou Z, Haghighi K, Green L, Mantzoros CS, Hajjar RJ, Tranter M, Karakikes I, Kranias EG, Stillitano F, Kafasla P*, Sanoudou D*. 2022, "Isoform changes of action potential regulators in the ventricles of arrhythmogenic phospholamban-R14del humanized mouse hearts.", Metabolism., 2022 Nov 11: 155344. doi: 10.1016/j.metabol.2022.155344. *equal contribution [PubMed].

Birladeanu A-M, Rogalska M, Potiri M, Papadaki V, Andreadou M, Kontoyiannis DL, Lewis JD, Erpapazoglou Z, Kafasla P. 2021, "The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells.", Oncogene, 1–15 [PubMed].

Skliris A, Papadaki O, Kafasla P, Karakasiliotis I, Hazapis O, Reczko M, Grammenoudi S, Bauer J, Kontoyiannis DL. (2015) Neuroprotection requires the functions of the RNA-binding protein HuR. Cell Death Differ. 22:703-718 https://www.ncbi.nlm.nih.gov/pubmed/25301069

Mickleburgh I, *Kafasla P, Cherny D, Llorian M, Curry S, Jackson RJ, Smith CWJ. (2014) The organization of RNA contacts by PTB for regulation of FAS splicing. Nucl. Acids. Res.42:8605-8620 *co-corresponding and joined first author https://www.ncbi.nlm.nih.gov/pubmed/24957602

Kafasla P, Skliris A, Kontoyiannis DL (2014) Post-transcriptional coordination of immunological responses by RNA-binding proteins. Nat. Immunol. 15:492-502 https://www.ncbi.nlm.nih.gov/pubmed/24840980

Kafasla P, Karakasiliotis I, Kontoyiannis DL. (2012) Decoding the functions of post-transcriptional regulators in the determination of inflammatory states: focus on macrophage activation. Wiley Interdiscip Rev Syst Biol Med 4:509-523 https://www.ncbi.nlm.nih.gov/pubmed/22761012

Kafasla P, Mickleburgh I, Llorian M, Coelho M, Gooding C, Cherny D, Joshi A, Kotik-Kogan O, Curry S, Eperon IC, Jackson RJ, Smith CWJ. (2012) Defining the roles and interactions of PTB. Biochem Soc Trans 40:815-820
https://www.ncbi.nlm.nih.gov/pubmed/22817740

Yu Y, Sweeney TR, Kafasla P, Jackson RJ, Pestova TV, Hellen CU. (2011) The mechanism of translation initiation on Aichivirus RNA mediated by a novel type of picornavirus IRES. EMBO J. 30: 4423-4436
https://www.ncbi.nlm.nih.gov/pubmed/21873976

Kafasla P, Lin H, Curry S, Jackson RJ. (2011) Activation of picornaviral IRESs by PTB shows differential dependence on each PTB RNA-binding domain. RNA 17:1120-1131 https://www.ncbi.nlm.nih.gov/pubmed/21518806

Kafasla P, Morgner N,Robinson C, Jackson RJ. (2010) Polypyrimidine tract binding protein stimulates the poliovirus IRES by modulating eIF4G binding. EMBO J. 29:3710-3722 https://www.ncbi.nlm.nih.gov/pubmed/20859255

*Kafasla P, Barrass JD, Thompson E, Fromont-Racine M, Jacquier A, Beggs JD, Lewis J. (2009) Interaction of yeast eIF4G with spliceosome components: implications in pre-mRNA processing events. RNA Biol 6:563-574 *corresponding author https://www.ncbi.nlm.nih.gov/pubmed/19838078

Kafasla P, Morgner N,Pöyry TAA, Curry S, Robinson C, Jackson RJ. (2009) Polypyrimidine tract binding protein stabilizes the encephalomyocarditis virus IRES structure via binding multiple sites in a unique orientation. Molecular Cell 34:556-568 https://www.ncbi.nlm.nih.gov/pubmed/19524536

ApostolakiΑ, ErpapazoglouΖ, HarispeL, BilliniΜ, KafaslaP, KizisD, PenalvaΜ, ScazzocchioC, SophianopoulouV. (2009) AgtA, the dicarboxylic amino acid transporter of Aspergillus nidulans, is concertedly down-regulated by exquisite sensitivity to nitrogen metabolite repression and ammonium-elicited endocytosis. Eukaryotic Cell 8:339-352 https://www.ncbi.nlm.nih.gov/pubmed/19168757

Kafasla P, Bouzarelou D, Frillingos S, Sophianopoulou V. (2007) The proline permease of Aspergillus nidulans: functional replacement of the native cysteine residues and properties of a cysteine-less transporter. Fungal Genet Biol. 44:615-626 https://www.ncbi.nlm.nih.gov/pubmed/17350864

Erpapazoglou Z, Kafasla P, Sophianopoulou V. (2006) The product of the SHR3 orthologue of Aspergillus nidulans has restricted range of amino acid transporter targets. Fungal Genet Biol. 43:222-233
https://www.ncbi.nlm.nih.gov/pubmed/16531082

Kafasla P, Patrinou-Georgoula M, Lewis JD, Guialis A. (2002) Differential binding of polypeptides of the hnRNP M family to pre-mRNA during RNA spliceosome assembly. Biochem J. 363:793-799
https://www.ncbi.nlm.nih.gov/pubmed/11964181

Kafasla P, Patrinou-Georgoula M, Guialis A. (2000) The 72/74 kDa polypeptides of the 70-110S large heterogeneous nuclear ribonucleoprotein complex (LH-nRNP) represent a discrete subset of the hnRNP M protein family. Biochem J. 350:495-503 https://www.ncbi.nlm.nih.gov/pubmed/10947964