BSRC "Alexander Fleming" Publications

2022 - (58)

Martens A, Hertens P, Priem D, Rinotas V, Meletakos T, Gennadi M, Van Hove L, Louagie E, Coudenys J, De Muynck A, Gaublomme D, Sze M, van Hengel J, Catrysse L, Hoste E, Zajac JD, Davey RA, Van Hoorebeke L, Hochepied T, Bertrand MJM, Armaka M, Elewaut D, van Loo G. 2022, "A20 controls RANK-dependent osteoclast formation and bone physiology.", EMBO Rep., 2022 Dec 6; 23(12):e55233. doi: 10.15252/embr.202255233. [PubMed].

Kyriaki Katsaounou, Elpiniki Nicolaou, Paris Vogazianos, Cameron Brown, Marios Stavrou, Savvas Teloni, Pantelis Hatzis, Agapios Agapiou, Elisavet Fragkou, Georgios Tsiaoussis, George Potamitis, Apostolos Zaravinos, Chrysafis Andreou, Athos Antoniades, Christos Shiammas, Yiorgos Apidianakis. 2022/span>, "Colon Cancer: From Epidemiology to Prevention., Metabolites., 2022 May 30; 12(6):499. doi: 10.3390/metabo12060499. [PubMed].

Ross-Hellauer T, Klebel T, Bannach-Brown A, Horbach SP, Jabeen H, Manola N, Metodiev T, Papageorgiou H, Reczko M, Sansone S-A, Schneider J, Tijdink J, Vergoulis T. 2022, "TIER2: enhancing Trust, Integrity and Efficiency in Research through next-level Reproducibility.", Research Ideas and Outcomes, 8: e98457 [DOI].

Carr T, McGregor S, Dias S, Verykokakis M, Le Beau MM, Xue HH, Sigvardsson M, Bartom ET, Kee BL. 2022, "Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in E2a-/- T Acute Lymphoblastic Leukemia", Front Immunol., 2022 Mar 18; 13:845488. doi: 10.3389/fimmu.2022.845488. [PubMed].

Vassilopoulos N, Kaplanian A, Vinos M, Katsaiti Y, Christodoulou R, Denaxa M, Skaliora I. 2022, "The role of selective Satb1 deletion in somatostatin expressing interneurons on endogenous network activity and the transition to epilepsy.", J Neurosc. Res., 2023 Apr; 101(4):424-447. doi: 10.1002/jnr.25156. Epub 2022 Dec 21 [PubMed].

Asgarian Z, Oliveira MG, Stryjewska A, Maragkos I, Rubin AN, Magno L, Pachnis V, Ghorbani M, Hiebert SW, Denaxa M, Kessaris N. 2022, "MTG8 interacts with LHX6 to specify cortical interneuron subtype identity.", Nat Commun. , 2022 Sep 5; 13(1):5217. doi: 10.1038/s41467-022-32898-6. [PubMed].

Kalemaki K, Velli A, Christodoulou O, Denaxa M, Karagogeos D, Sidiropoulou K. 2022, "The developmental changes in intrinsic and synaptic properties of prefrontal neurons enhance local network activity from the second to the third postnatal weeks in mice.", Cereb Cortex. , 2022 Aug 22; 32(17):3633-3650. doi: 10.1093/cercor/bhab438. [PubMed].

Christodoulou O, Maragkos I, Antonakou V, Denaxa M. 2022, "The development of MGE-derived cortical interneurons: An Lhx6 tale.", Int J Dev Biol. , 2022; 66(1-2-3):43-49. doi: 10.1387/ijdb.210185md. [PubMed].

Arapatzi C, Rouni G, Kostourou V. 2022, "Vascular cell-matrix adhesion in development and cancer.", Int J Dev Biol., 2022;66(1-2-3) :103-113. doi: 10.1387/ijdb.210204vk. [PubMed].

Manolakou T, Nikolopoulos D, Gkikas D, Filia A, Samiotaki M, Stamatakis G, Fanouriakis A, Politis P, Banos A, Alissafi T, Verginis P, Boumpas DT. 2022, "ATR-mediated DNA damage responses underlie aberrant B cell activity in systemic lupus erythematosus.", Sci Adv., 2022 Oct 28; 8(43):eabo5840. doi: 10.1126/sciadv.abo5840. Epub 2022 Oct 28. [PubMed].

Pappa E, Vastardis H, Makridakis M, Zoidakis J, Vougas K, Stamatakis G, Samiotaki M, Rahiotis C. 2022, "Analysis of Human and Microbial Salivary Proteomes in Children Offers Insights on the Molecular Pathogenesis of Molar-Incisor Hypomineralization.", Biomedicines., 2022 Aug 24; 10(9):2061. doi: 10.3390/biomedicines10092061. [PubMed].

Prifti E, Tsakiri EN, Vourkou E, Stamatakis G, Samiotaki M, Skoulakis EMC, Papanikolopoulou K. 2022, "Mical modulates Tau toxicity via cysteine oxidation in vivo.", Acta Neuropathol Commun., 2022 Apr 4; 10(1):44. doi: 10.1186/s40478-022-01348-1. [PubMed].

Katsarou K, Adkar-Purushothama CR, Tassios E, Samiotaki M, Andronis C, Lisón P, Nikolaou C, Perreault JP, Kalantidis K. 2022, "Revisiting the Non-Coding Nature of Pospiviroids.", Cells., 2022 Jan 13; 11(2):265. doi: 10.3390/cells11020265. [PubMed].

Xanthopoulou A, Moysiadis T, Bazakos C, Karagiannis E, Karamichali I, Stamatakis G, Samiotaki M, Manioudaki M, Michailidis M, Madesis P, Ganopoulos I, Molassiotis A, Tanou G. 2022, "The perennial fruit tree proteogenomics atlas: a spatial map of the sweet cherry proteome and transcriptome.", Plant J., 2022 Mar; 109(5):1319-1336. doi: 10.1111/tpj.15612. Epub 2021 Dec 16. [PubMed].

Vasilopoulou E, Giannakopoulou A, Kapsalis C, Michou M, Michoglou-Sergiou A, Kolisis FN, Skretas G. 2022, "Second-Generation Escherichia coli SuptoxR Strains for High-Level Recombinant Membrane Protein Production.", ACS Synthetic Biology., 2022 Aug 19; 11(8):2599-2609. [PubMed].

Koliaraki V, Dotto GP, Buckley CD, Kollias G. 2022, "Mesenchymal cells in health and disease", Nat Immunol., 23(10): 1395-1398. [PubMed].

Tzaferis C, Karatzas E, Baltoumas FA, Pavlopoulos GA, Kollias G, Konstantopoulos D. 2022, "SCALA: A web application for multimodal analysis of single cell next generation sequencing data", bioRxiv, [doi].

Yan M, Komatsu N, Muro R, Huynh NCN, Tomofuji Y, Okada Y, Suzuki HI, Takaba H, Kitazawa R, Kitazawa S, Pluemsakunthai W, Mitsui Y, Satoh T, Okamura T, Nitta T, Im SH, Kim CJ, Kollias G, Tanaka S, Okamoto K, Tsukasaki M, Takayanagi H. 2022, "ETS1 governs pathological tissue-remodeling programs in disease-associated fibroblasts", Nat Immunol. , doi: 10.1038/s41590-022-01285-0 [PubMed].

Papadopoulou D, Roumelioti F, Tzaferis C, Chouvardas P, Pedersen AK, Charalampous F, Christodoulou-Vafeiadou E, Ntari L, Karagianni N, Denis M, Olsen JV, Matralis AN, Kollias G. 2022, "Repurposing of Amisulpride, a known antipsychotic drug, to target synovial fibroblasts activation in arthritis", bioRxiv, [doi].

Armaka M, Konstantopoulos D, Tzaferis C, Lavigne MD, Sakkou M, Liakos A, Sfikakis PP, Dimopoulos MA, Fousteri M & Kollias G. 2022, "Single-cell multimodal analysis identifies common regulatory programs in synovial fibroblasts of rheumatoid arthritis patients and modeled TNF-driven arthritis.", Genome Med. , 14(1) :78. [PubMed].

Roumelioti F, Tzaferis C, Konstantopoulos D, Papadopoulou D, Prados A, Sakkou M, Liakos A, Chouvardas P, Meletakos T, Pandis Y, Karagianni N, Denis M, Fousteri M, Armaka M, Kollias G. 2022, "miR-221/222 drive synovial fibroblast expansion and pathogenesis of TNF-mediated arthritis", bioRxiv, [doi].

Koliaraki V, Dotto GP, Buckley CD, Kollias G. 2022, "Mesenchymal cells in health and disease", Nat Immunol., 23(10): 1395-1398. [PubMed].

Taze C, Drakouli S, Samiotaki M, Panayotou G, Simos G, Georgatsou E, Mylonis I. 2022, "Short-term hypoxia triggers ROS and SAFB mediated nuclear matrix and mRNA splicing remodeling.", Redox Biol., 2022 Nov 17; 58:102545. doi: 10.1016/j.redox.2022.102545. Online ahead of print. [PubMed].

Rogalska ME, Vafiadaki E, Erpapazoglou Z, Haghighi K, Green L, Mantzoros CS, Hajjar RJ, Tranter M, Karakikes I, Kranias EG, Stillitano F, Kafasla P*, Sanoudou D*. 2022, "Isoform changes of action potential regulators in the ventricles of arrhythmogenic phospholamban-R14del humanized mouse hearts.", Metabolism., 2022 Nov 11: 155344. doi: 10.1016/j.metabol.2022.155344. *equal contribution [PubMed].

Drosouni A, Panagopoulou M, Aidinis V, Chatzaki E. 2022, "Autotaxin in Breast Cancer: Role, Epigenetic Regulation and Clinical Implications.", Cancers., 2022 Nov 4; 14(21):5437 [PubMed].

Vourkou E, Paspaliaris V, Bourouliti A, Zerva MC, Prifti E, Papanikolopoulou K, Skoulakis EMC. 2022, "Differential Effects of Human Tau Isoforms to Neuronal Dysfunction and Toxicity in the Drosophila CNS", Int J Mol Sci., 2022 Oct 26;23(21):12985. doi: 10.3390/ijms232112985. [PubMed].

Armakolas A, Dimopoulou V, Nezos A, Stamatakis G, Samiotaki M, Panayotou G, Tampaki M, Stathaki M, Dourakis S, Koskinas J. 2022, "Cellular, Molecular and Proteomic Characteristics of Early Hepatocellular Carcinoma.", Curr Issues Mol Biol. , 2022 Oct 10; 44(10):4714-4734. doi: 10.3390/cimb44100322 [PubMed].

Georgiou-Siafis SK, Samiotaki MK, Demopoulos VJ, Panayotou G, Tsiftsoglou AS. 2022, "Glutathione-Hemin/Hematin Adduct Formation to Disintegrate Cytotoxic Oxidant Hemin/Hematin in Human K562 Cells and Red Blood Cells' Hemolysates: Impact of Glutathione on the Hemolytic Disorders and Homeostasis.", Antioxidants (Basel)., 2022 Sep 30; 11(10):1959. doi: 10.3390/antiox11101959 [PubMed].

Theodosia Charitou, Panagiota I. Kontou, Ioannis A. Tamposis, Georgios A. Pavlopoulos, Georgia G. Braliou, Pantelis G. Bagos. 2022, "Drug genetic associations with COVID-19 manifestations: a data mining and network biology approach.", Pharmacogenomics J, 2022 Sep 28, doi: 10.1038/s41397-022-00289-1 [PubMed].

Papadaki G, Goutakoli P, Tiniakou I, Grün JR, Grützkau A, Pavlopoulos GA, Iliopoulos I, Bertsias G, Boumpas D, Ospelt C, Reizis B, Sidiropoulos P, Verginis P. 2022, "IL-6 Signaling Attenuates TNF-α Production by Plasmacytoid Dendritic Cells in Rheumatoid Arthritis.", J Immunol, 2022 Sep 23:, ji2100882. doi: 10.4049/jimmunol.2100882. Online ahead of print. [PubMed].

Baltsavia I., Theodosiou T., Papanikolaou N., Pavlopoulos GA., Amoutzias GD., Panagopoulou M., Chatzaki E., Andreakos E., Iliopoulos I. 2022, "Prediction and Ranking of Biomarkers Using multiple UniReD", Int J Mol Sci., 2022 Sep 21;23(19):11112. doi: 10.3390/ijms231911112. [PubMed].

Foka K, Georganta EM, Semelidou O, Skoulakis EMC. 2022, "Loss of the Schizophrenia-linked Furin protein from Drosophila mushroom body neurons results in antipsychotic-reversible habituation deficits.", J Neurosci., 2022 Aug 25; 42(39):7496-511. [PubMed].

Bourouliti A, Skoulakis EMC. 2022, "Anesthesia Resistant Memories in Drosophila, a Working Perspective.", Int J Mol Sci., 2022 Jul 31;, 23(15):8527. doi: 10.3390/ijms23158527 [PubMed].

Magkrioti C, Antonopoulou G, Fanidis D, Pliaka V, Sakellaropoulos T, Alexopoulos LG, Ullmer C, Aidinis V. 2022, "Lysophosphatidic Acid Is a Proinflammatory Stimulus of Renal Tubular Epithelial Cells", Int J Mol Sci., 2022 Jul 5;, 23(13):7452 [PubMed].

Kleio-Maria Verrou, Georgios A. Pavlopoulos, Panagiotis Moulos. 2022, "Protocol for unbiased, consolidated variant calling from whole exome sequencing data", STAR Protocοls, 2022 May 30;, 3(2):101418. doi: 10.1016/j.xpro.2022.101418. eCollection 2022 Jun 17 [PubMed].

Karshovska E, Mohibullah R, Zhu M, Zahedi F, Thomas D, Magkrioti C, Geissler C, Megens RTA, Bianchini M, Nazari-Jahantigh M, Ferreirós N, Aidinis V., Schober A. 2022, "ENPP2 Increases Atherosclerosis in Female and Male Mice.", Arterioscler Thromb Vasc Biol., 2022 Jun 16 , [PubMed].

Enrico Ne, Raquel Crespo, Ray Izquierdo-Lara, Shringar Rao, Selin Koçer, Alicja Górska, Thomas van Staveren, Tsung Wai Kan, David van de Vijver, Dick Dekkers, Casper Rokx, Panagiotis Moulos, Pantelis Hatzis, Robert-Jan Palstra, Jeroen Demmers, Tokameh Mahmoudi. 2022, "Catchet-MS identifies IKZF1-targeting thalidomide analogues as novel HIV-1 latency reversal agents", Nucleic Acids Res, 2022 Jun 10; 50(10):5577-5598. doi: 10.1093/nar/gkac407. [PubMed].

Bourouliti A, Skoulakis EMC. 2022, "Cold Shock Disrupts Massed Training-Elicited Memory in Drosophila.", Int J Mol Sci., 2022 Jun 8;, 23(12):6407. doi: 10.3390/ijms23126407 [PubMed].

Galanis A., Vardakas P., Reczko M., Harokopos V., Hatzis P., Skoulakis E., Pavlopoulos GA., Patalano S. 2022, "Bee foraging preferences, microbiota and pathogens revealed by direct shotgun metagenomics of honey", Molecular Ecology Resources, 2022 May 20. , doi: 10.1111/1755-0998.13626 [PubMed].

Karatzas E., Koutrouli M., Baltoumas F., Papanikolopoulou K., Bouyioukos C., Pavlopoulos GA, 2022, "The network makeup artist (NORMA-2.0): Distinguishing annotated groups in a network using innovative layout strategies", Bioinformatics Advances, 13 May 2022;, doi:10.1093/bioadv/vbac036 .

Panagopoulou M, Drosouni A, Fanidis D, Karaglani M, Balgkouranidou I, Xenidis N, Aidinis V., Chatzaki E. 2022, "ENPP2 Promoter Methylation Correlates with Decreased Gene Expression in Breast Cancer: Implementation as a Liquid Biopsy Biomarker", Int J Mol Sci., 2022 Mar 28; , 23(7):3717. [PubMed].

Hilke Ehlich, Heather L Cater, Ann M Flenniken, Isabelle Goncalves Da Cruz, Anne-Marie Mura, Vasileios Ntafis, Michael Raess, Mohammed Selloum, Claudia Stoeger, Sarka Suchanova, Reetta Vuolteenaho, Steve D M Brown, Yann Hérault, Reetta Hinttala, Martin Hrabě de Angelis, George Kollias, Dimitris L Kontoyiannis, Bernard Malissen, Colin McKerlie, Radislav Sedláček, Sara E Wells, Ana Zarubica, Jan Rozman, Tania Sorg. 2022, "INFRAFRONTIER quality principles in systemic phenotyping", Mamm Genome., 2022 Mar; 33(1):120-122. doi: 10.1007/s00335-021-09892-2. Epub 2021 Jul 30. [PubMed].

Galaris A, Fanidis D, Stylianaki EA, Harokopos V, Kalantzi AS, Moulos P, Dimas AS, Hatzis P, Aidinis V.. 2022, "Obesity Reshapes the Microbial Population Structure along the Gut-Liver-Lung Axis in Mice", Biomedicines., 2022 Feb 19; 10(2):494 [PubMed].

Antoniou N, Prodromidou K, Kouroupi G, Boumpoureka I, Samiotaki M, Panayotou G, Xilouri M, Kloukina I, Stefanis L, Grailhe R, Taoufik E, Matsas R. 2022, "High content screening and proteomic analysis identify a kinase inhibitor that rescues pathological phenotypes in a patient-derived model of Parkinson's disease.", NPJ Parkinsons Dis., 2022 Feb 11; 8(1):15. doi: 10.1038/s41531-022-00278-y. [PubMed].

Sofia Gargani, Niki Lourou, Christina Arapatzi, Dimitris Tzanos, Marania Saridaki, Esmeralda Dushku, Margarita Chatzimike, Nikolaos D Sidiropoulos, Margarita Andreadou, Vasileios Ntafis, Pantelis Hatzis, Vassiliki Kostourou, Dimitris L Kontoyiannis. 2022, "Inactivation of AUF1 in Myeloid Cells Protects From Allergic Airway and Tumor Infiltration and Impairs the Adenosine-Induced Polarization of Pro-Angiogenic Macrophages", Front Immunol., 2022 Feb 11 13:752215. doi: 10.3389/fimmu.2022.752215. eCollection 2022. [PubMed].

Temponeras I, Stamatakis G, Samiotaki M, Georgiadis D, Pratsinis H, Panayotou G, Stratikos E. 2022, "ERAP2 Inhibition Induces Cell-Surface Presentation by MOLT-4 Leukemia Cancer Cells of Many Novel and Potentially Antigenic Peptides.", Int J Mol Sci. , 2022 Feb 8; 23(3):1913. doi: 10.3390/ijms23031913 [PubMed].

Karra AG, Sioutopoulou A, Gorgogietas V, Samiotaki M, Panayotou G, Psarra AG. 2022, "Proteomic analysis of the mitochondrial glucocorticoid receptor interacting proteins reveals pyruvate dehydrogenase and mitochondrial 60 kDa heat shock protein as potent binding partners.", J Proteomics., 2022 Apr 15; 257:104509. doi: 10.1016/j.jprot.2022.104509. Epub 2022 Feb 4. [PubMed].

Chandris P, Giannouli CC, Panayotou G, . 2022, "Imaging Approaches for the Study of Metabolism in Real Time Using Genetically Encoded Reporters.", Front Cell Dev Biol., 2022 Jan 18; 9:725114. doi: 10.3389/fcell.2021.725114. eCollection 2021. [PubMed].

Dimitra Kerdidani, Emmanouil Aerakis, Kleio-Maria Verrou, Ilias Angelidis, Katerina Douka, Maria-Anna Manio, Petros Stamoulis, Katerina Goudevenou, Alejandro Prados, Christos Tzaferis, Vasileios Ntafis, Ioannis Vamvakaris, Evangelos Kaniaris, Konstantinos Vachlas, Evangelos Sepsas, Anastasios Koutsopoulos, Konstantinos Potaris, Maria Tsoumakidou. 2022, "Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts", J Exp Med, 022 Feb 7; 219(2):e20210815. doi: 10.1084/jem.20210815. Epub 2022 Jan 14. [PubMed].

Vasiliki-Iris Perivolidi, Foteini Violitzi, Elisavet Ioannidou, Vagelis Rinotas, George Stamatakis, Martina Samiotaki, George Panayotou, Eleni Douni. 2022, "Proteomic Identification of the SLC25A46 Interactome in Transgenic Mice Expressing SLC25A46-FLAG", J Proteome Res, 2022 Jan 5 doi: 10.1021/acs.jproteome.1c00728. Online ahead of print. [PubMed].

Nikitopoulou I, Katsifa A, Kanellopoulou P, Jahaj E, Vassiliou AG, Mastora Z, Dimopoulou I, Orfanos SE, Aidinis V, Kotanidou A. 2022, "Autotaxin Has a Negative Role in Systemic Inflammation", Int J Mol Sci., 2022; 23(14):7920 [PubMed].

Kalamatianos T, Drosos E, Magkrioti C, Nikitopoulou I, Koutsarnakis C, Kotanidou A, Paraskevas GP, Aidinis V, Stranjalis G. 2022, "Autotaxin Activity in Chronic Subdural Hematoma: A Prospective Clinical Study", Diagnostics., 2022; 12(8):1865 [PubMed].

Selvitopi O., Ekanayake S., Guidi G., Awan M., Pavlopoulos GA., Azad A., Kyrpides N., Oliker L., Yelick K., Buluç A. 2022, "Extreme-scale many-against-many protein similarity search", ΙΕΕΕ, SC22: International Conference for High Performance Computing, Networking, Storage and Analysis, Dallas, TX, US, 2022 pp. 1-12. Nominated for the ACM Gordon Bell Prize award , LINK.

Yan M, Komatsu N, Muro R, Huynh NCN, Tomofuji Y, Okada Y, Suzuki HI, Takaba H, Kitazawa R, Kitazawa S, Pluemsakunthai W, Mitsui Y, Satoh T, Okamura T, Nitta T, Im SH, Kim CJ, Kollias G, Tanaka S, Okamoto K, Tsukasaki M, Takayanagi H. 2022, "ETS1 governs pathological tissue-remodeling programs in disease-associated fibroblasts", Nat Immunol. , doi: 10.1038/s41590-022-01285-0 [PubMed].

Armaka M, Konstantopoulos D, Tzaferis C, Lavigne MD, Sakkou M, Liakos A, Sfikakis PP, Dimopoulos MA, Fousteri M & Kollias G. 2022, "Single-cell multimodal analysis identifies common regulatory programs in synovial fibroblasts of rheumatoid arthritis patients and modeled TNF-driven arthritis.", Genome Med. , 14(1) :78. [PubMed].

Bothos E, Hatzis P, Moulos P. 2022, "Interactive Analysis, Exploration, and Visualization of RNA-Seq Data with SeqCVIBE", Methods Protoc, 2022, 5(2):27. [PubMed].

Kiparaki M, Khan C, Folgado-Marco V, Chuen J, Moulos P, Baker NE. 2022, "The transcription factor Xrp1 orchestrates both reduced translation and cell competition upon defective ribosome assembly or function", eLife, 2022, 11: e71705 [PubMed].

Evangelos Karatzas, Fotis A. Baltoumas, Ioannis Kasionis, Despina Sanoudou, Aristides G. Eliopoulos, Theodosios Theodosiou, Ioannis Iliopoulos, Georgios A. Pavlopoulos. 2022, "Darling: A Web Application for Detecting Disease-Related Biomedical Entity Associations with Literature Mining", Biomolecules, 12, no. 4: 520. [doi], [Link], [PubMed].

Zafeiropoulos, Haris, Savvas Paragkamian, Stelios Ninidakis, Georgios A. Pavlopoulos, Lars J. Jensen, and Evangelos Pafilis. 2022, "PREGO: A Literature and Data-Mining Resource to Associate Microorganisms, Biological Processes, and Environment Types", Microorganisms, 10, no. 2: 293. [doi], [PubMed].