BSRC "Alexander Fleming" Publications

2020 - (28)

Martens A, Priem D, Hoste E, Vetters J, Rennen S, Catrysse L, Voet S, Deelen L, Sze M, Vikkula H, Slowicka K, Hochepied T, Iliaki K, Wullaert A, Janssens S, Lamkanfi M, Beyaert R, Armaka M, Bertrand MJM, van Loo G. 2020, "Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities.", Nat Immunol., 2020 Apr; 21(4):381-387. doi: 10.1038/s41590-020-0621-9. Epub 2020 Mar 16. [PubMed].

Karagianni P, Moulos P, Odom D, Talianidis I. 2020, "Bookmarking by non-pioneer transcription factors during liver development establishes competence for future gene activation", Cell Rep., 30(5): 1319-1328.e61 [PubMed].

Koliaraki V, Prados A, Armaka M, Kollias G. 2020, "The mesenchymal context in inflammation, immunity and cancer.", Nat Immunol., 21(9): 974-982. Review. [PubMed].

Christodoulou-Vafeiadou E, Geka C, Ntari L, Kranidioti K, Argyropoulou E, Meier F, Armaka M, Mourouzis I, Pantos C, Rouchota M, Loudos G, Denis MC, Karagianni N, Kollias G. 2020, "Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis.", Arthritis Res Ther. , 22(1) :232 [PubMed].

Engie Prifti, Eleni N Tsakiri, Ergina Vourkou, George Stamatakis, Martina Samiotaki, Katerina Papanikolopoulou. 2020, "The two Cysteines of Tau protein are functionally distinct and contribute differentially to its pathogenicity in vivo", J Neurosci., 2020 Dec 15; JN-RM-1920-20. doi: 10.1523/JNEUROSCI.1920-20.2020. [PubMed].

Oriol de Barrios, Alexandros Galaras, Juan L Trincado, Alba Azagra, Olga Collazo, Ainara Meler, Antonio Agraz-Doblas, Clara Bueno, Paola Ballerini, Giovanni Cazzaniga, Ronald W Stam, Ignacio Varela, Paola De Lorenzo, Maria Grazia Valsecchi, Pantelis Hatzis, Pablo Menéndez, Maribel Parra. 2020, "HDAC7 is a major contributor in the pathogenesis of infant t(4;11) proB acute lymphoblastic leukemia", Leukemia, 2020 Dec 1. doi: 10.1038/s41375-020-01097-x. Online ahead of print. [PubMed].

Valeria Kaltezioti, Iosifina P Foskolou, Matthieu D Lavigne, Elpinickle Ninou, Matina Tsampoula, Maria Fousteri, Marigoula Margarity, Panagiotis K Politis. 2020, "Prox1 inhibits neurite outgrowth during central nervous system development", Cell Mol Life Sci., 2020 Nov 28. doi: 10.1007/s00018-020-03709-2 [PubMed].

Keramidis I, Vourkou E, Papanikolopoulou K, Skoulakis EMC. 2020, "Functional Interactions of Tau Phosphorylation Sites That Mediate Toxicity and Deficient Learning in Drosophila melanogaster.", Front Mol Neurosci. , 2020 Oct 21; 13:569520. [PubMed].

Magkrioti C, Kaffe E, Stylianaki EA, Sidahmet C, Melagraki G, Afantitis A, Matralis AN, Aidinis V. 2020, "Structure-Based Discovery of Novel Chemical Classes of Autotaxin Inhibitors.", Int J Mol Sci., 2020 Sep 23; 21(19):7002. [PubMed].

Oguz Selvitopi, Saliya Ekanayake, Giulia Guidi, Georgios A. Pavlopoulos, Ariful Azad, and Aydin Buluç. 2020, "Distributed many-to-many protein sequence alignment using sparse matrices", Proceedings of the 2020 ACM/IEEE International Conference for High Performance Computing, Networking, Storage and Analysis, SC’20 [Code | Article].

George Stamatakis, Martina Samiotaki, Anastasia Mpakali, George Panayotou, Efstratios Stratikos. 2020, "Generation of SARS-CoV-2 S1 Spike Glycoprotein Putative Antigenic Epitopes in Vitro by Intracellular Aminopeptidases", J Proteome Res. , 2020 Sep 22. doi: 10.1021/acs.jproteome.0c00457. Online ahead of print. [PubMed].

Semelidou O, Skoulakis EMC. 2020, "One size does not fit all in Drosophila olfactory habituation", Proc Natl Acad Sci U S A. , 2020 Aug 25; 117(34):20372. doi: 10.1073/pnas.2012622117 [PubMed].

Marianthi Gioulbasani, Alexandros Galaras, Sofia Grammenoudi, Panagiotis Moulos, Alexander L Dent, Mikael Sigvardsson, Pantelis Hatzis, Barbara L Kee, Mihalis Verykokakis . 2020, "The transcription factor BCL-6 controls early development of innate-like T cells", Nat Immunol., 2020 Sep; 21(9):1058-1069. doi: 10.1038/s41590-020-0737-y. Epub 2020 Jul 27 [PubMed].

Connor J. Cooper, Kaiyuan Zheng, Katherine W. Rush, Alexander Johs, Brian C. Sanders, Georgios A. Pavlopoulos, Nikos C. Kyrpides, Mircea Podar, Sergey Ovchinnikov, Stephen W. Ragsdale & Jerry M. Parks. 2020, "Structure determination of the HgcAB complex using metagenome sequence data: insights into microbial mercury methylation.", Communications Biology, 2020 Jun 19; 3(1):320. doi: 10.1038/s42003-020-1047-5 [PubMed].

Sandip Mukherjee, Ritesh Kumar, Elviche Tsakem Lenou, Venkatesha Basrur, Dimitris L. Kontoyiannis, Fotis Ioakeimidis, George Mosialos, Arianne L. Theiss, Richard A. Flavell & K. Venuprasad. 2020, "Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation.", Nature Immunology , (2020) doi: 10.1038/s41590-020-0681-x [Nature].

Gagliano T, Shah K, Gargani S, Lao L, Alsaleem M, Chen J, Ntafis V, Huang P, Ditsiou A, Vella V, Yadav K, Bienkowska K, Bresciani G, Kang K, Li L, Carter P, Benstead-Hume G, O'Hanlon T, Dean M, Pearl FM, Lee SC, Rakha EA, Green AR, Kontoyiannis DL, Song E, Stebbing J, Giamas G. 2020, "PIK3Cδ expression by fibroblasts promotes triple-negative breast cancer progression.", J Clin Invest. , 2020 May 11. pii: 128313. doi: 10.1172/JCI128313. [Epub ahead of print] [PubMed].

Georgiou-Siafis,S.K., Samiotaki,M.K., Demopoulos,V.J., Panayotou,G. , and Tsiftsoglou,A.S. 2020, "Forma- tion of novel N-acetylcysteine-hemin adducts abrogates hemin-induced cytotoxicity and suppresses the NRF2- driven stress response in human pro-erythroid K562 cells.", Eur. J. Pharmacol. , 173077 [PubMed].

Martens A, Priem D, Hoste E, Vetters J, Rennen S, Catrysse L, Voet S, Deelen L, Sze M, Vikkula H, Slowicka K, Hochepied T, Iliaki K, Wullaert A, Janssens S, Lamkanfi M, Beyaert R, Armaka M, Bertrand MJM, van Loo G. 2020, "Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities", Nat Immunol., 21(4):381-387 [PubMed].

Roulis M, Kaklamanos A, Schernthanner M, Bielecki P, Zhao J, Kaffe E, Frommelt LS, Qu R, Knapp MS, Henriques A, Chalkidi N, Koliaraki V, Jiao J, Brewer JR, Bacher M, Blackburn HN, Zhao X, Breyer RM, Aidinis V, Jain D, Su B, Herschman HR, Kluger Y, Kollias G, Flavell RA. 2020, "Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche.", Nature, 580(7804) :524-529. [PubMed].

Ninou I, Sevastou I, Magkrioti C, Kaffe E, Stamatakis G, Thivaios S, Panayotou G, Aoki J, Kollias G, Aidinis V. 2020, "Genetic deletion of Autotaxin from CD11b+ cells decreases the severity of experimental autoimmune encephalomyelitis.", PLoS One, 15(4) :e0226050 [PubMed].

Papanikolopoulou K, Skoulakis EMC. 2020, "Altered Proteostasis in Neurodegenerative Tauopathies", Adv Exp Med Biol., 2020;1233: 177-194. doi: 10.1007/978-3-030-38266-7_7. Review. [PubMed].

Theodosiou T, Papanikolaou N, Savvaki M, Bonetto G, Maxouri S, Fakoureli E, Eliopoulos GA, Tavernarakis N, Amoutzias GD, Pavlopoulos GA, Aivaliotis M, Nikoletopoulou V, Tzamarias D, Karagogeos D, Iliopoulos I. 2020, "UniProt Related Documents (UniReD): assisting wet lab biologists in their quest on finding novel counterparts in a protein network", NAR Genomics and Bioinformatics, Volume 2, Issue 1, March 2020, lqaa005 https://doi.org/10.1093/nargab/lqaa005 [Link].

Koliaraki V, Henriques A, Prados A, Kollias G. 2020, "Unfolding innate mechanisms in the cancer microenvironment: The emerging role of the mesenchyme.", J Exp Med., 217 (4). [PubMed].

Liakos A, Konstantopoulos D, Lavigne MD, Fousteri M. 2020, "Continuous transcription initiation guarantees robust repair of all transcribed genes and regulatory regions", Nature Communications, 11 Article number: 916, 14 February 2020, DOI: 10.1038/s41467-020-14566-9 [PubMed].

Koutrouli M, Karatzas E, Paez-Espino D, Pavlopoulos GA. 2020, "A Guide to Conquer the Biological Network Era Using Graph Theory", Frontiers in Bioengineering and Biotechnology, 2020;8:34. Published 2020 Jan 31. doi:10.3389/fbioe.2020.00034 [PubMed].

Sevastou I, Ninou I, and Aidinis V. 2020, "ATX expression from GFAP+ cells is essential for embryonic development", bioRxiv, , Jan 17, 2020. doi: 10.1101/2020.01.17.910141 [bioRxiv].

Gerokonstantis DT, Nikolaou A, Magkrioti C, Afantitis A, Aidinis V, Kokotos G, Moutevelis-Minakakis P. 2020, "Synthesis of novel 2-pyrrolidinone and pyrrolidine derivatives and study of their inhibitory activity against autotaxin enzyme", Bioorg Med Chem. , Jan 15; 28(2):115216. [PubMed].

Koutrouli M, Hatzis P, Pavlopoulos GA. 2020, "Exploring networks in the STRING & REACTOME database", in Systems Medicine: Integrative, Qualitative and Computational Approaches. Reference Module in Biomedical Sciences, 13 January 2020 ISBN:9780128012383, doi:0.1016/B978-0-12-801238-3.11516-8 [Link].