BSRC "Alexander Fleming" Publications

2019 - (34)

Spella M, Lilis I, Pepe MA, Chen Y, Armaka M, Lamort AS, Zazara DE, Roumelioti F, Vreka M, Kanellakis NI, Wagner DE, Giannou AD, Armenis V, Arendt KA, Klotz LV, Toumpanakis D, Karavana V, Zakynthinos SG, Giopanou I, Marazioti A, Aidinis V, Sotillo R, Stathopoulos GT. 2019, "Club cells form lung adenocarcinomas and maintain the alveoli of adult mice.", Elife, 2019 May 29; 8. pii: e45571. doi: 10.7554/eLife.45571. [PubMed].

Daras G, Rigas S, Alatzas A, Samiotaki M, Chatzopoulos D, Tsitsekian D, Papadaki V, Templalexis D, Banilas G, Athanasiadou AM, Kostourou V, Panayotou G, Hatzopoulos P. 2019, "LEFKOTHEA Regulates Nuclear and Chloroplast mRNA Splicing in Plants.", Dev Cell., 2019 Sep 23; 50(6):767-779.e7. doi: 10.1016/j.devcel.2019.07.024. Epub 2019 Aug 22. [PubMed].

Pedrosa AR, Bodrug N, Gomez-Escudero J, Carter EP, Reynolds LE, Georgiou PN, Fernandez I, Lees DM, Kostourou V, Alexopoulou AN, Batista S, Tavora B, Serrels B, Parsons M, Iskratsch T, Hodivala-Dilke KM. 2019, "Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and -861.", Cancer Res., 2019 Sep 1; 79(17):4371-4386. doi: 10.1158/0008-5472.CAN-18-3934. Epub 2019 Jun 12. [PubMed].

Buffin-Meyer B, Klein J, van der Zanden LFM., Levtchenko E, Moulos P, Lounis N, Conte-Auriol F, Hindryckx A, Wühl E, Persico N, Oepkes D, Schreuder MF, Tkaczyk M, Ariceta G, Fossum M, Parvex P, Feitz W, Olsen H, Montini G, Decramer S, Schanstra JP, ANTENATAL Consortium. 2019, "The ANTENATAL multicentre study to predict postnatal renal outcome in fetuses with posterior urethral valves: objectives and design", Clin Kidney J., 2019, 13(3):371-379 [PubMed].

Lourou N, Gavriilidis M, Kontoyiannis DL, . 2019, "Lessons from studying the AU-rich elements in chronic inflammation and autoimmunity.", J Autoimmun. , 2019 Nov; 104:102334. doi: 10.1016/j.jaut.2019.102334. Epub 2019 Oct 8. Review [PubMed].

Janice Sánchez B, Tremblay AK, Leduc-Gaudet JP, Hall DT, Kovacs E, Ma JF, Mubaid S, Hallauer PL, Phillips BL, Vest KE, Corbett AH, Kontoyiannis DL, Hussain SNA, Hastings KEM, Di Marco S, Gallouzi IE. 2019, "Depletion of HuR in murine skeletal muscle enhances exercise endurance and prevents cancer-induced muscle atrophy.", Nat Commun. , 2019 Sep 13; 10(1):4171. doi: 10.1038/s41467-019-12186-6. [PubMed].

Papadaki M, Rinotas V, Violitzi F, Thireou T, Panayotou G , Samiotaki M , Douni E. 2019, "New Insights for RANKL as a Proinflammatory Modulator in Modeled Inflammatory Arthritis", Frontiers in Immunology, : 10:97. 2019 [PubMed].

Marazioti A, Papadia K, Kannavou M, Spella M, Basta A, de Lastic AL, Rodi M, Mouzaki A, Samiotaki M, Panayotou G, Stathopoulos GT, Antimisiaris SG. 2019, "Cellular Vesicles: New Insights in Engineering Methods, Interaction with Cells and Potential for Brain Targeting", J Pharmacol Exp Ther., 370(3):772-785. 2019 [PubMed].

Daras G, Rigas S, Alatzas A, Samiotaki M, Chatzopoulos D, Tsitsekian D, Papadaki V, Templalexis D, Banilas G, Athanasiadou AM, Kostourou V, Panayotou G, Hatzopoulos P. 2019, "LEFKOTHEA Regulates Nuclear and Chloroplast mRNA Splicing in Plants", Developmental Cell. , 12. pii: S1534-5807(19)30630-6. 2019 [PubMed].

Foteini Violitzi, Vasiliki-Iris Perivolidi, Trias Thireou, Ioannis Grivas, Sylva Haralambous, Martina Samiotaki, George Panayotou, Eleni Douni. 2019, "Mapping interactome networks of DNAJC11, a novel mitochondrial protein causing neuromuscular pathology in mice", J Proteome Res. , 18(11): 3896-3912. 2019 [PubMed].

Paez-Espino D, Zhou J, Roux S, Nayfach S, Pavlopoulos GA, Schulz F, McMahon KD, Walsh D, Woyke T, Ivanova NN, Eloe-Fadrosh EA, Tringe SG, Kyrpides NC. 2019, "Diversity, evolution, and classification of virophages uncovered through global metagenomics", Microbiome., 2019 Dec 10; 7(1):157. doi: 10.1186/s40168-019-0768-5 [PubMed].

Nikitopoulou I, Manitsopoulos N, Kotanidou A, Tian X, Petrovic A, Magkou C, Ninou I, Aidinis V, Schermuly RT, Kosanovic D, Orfanos SE. 2019, "Orotracheal treprostinil administration attenuates bleomycin induced lung injury, vascular remodeling, and fibrosis in mice", Pulm Circ. , 2019 Nov 15; 9(4):204589401988195 [PubMed].

Heichler C, Scheibe K, Schmied A, Geppert CI, Schmid B, Wirtz S, Thoma OM, Kramer V, Waldner MJ, Büttner C, Farin HF, Pešić M, Knieling F, Merkel S, Grüneboom A, Gunzer M, Grützmann R, Rose-John S, Koralov SB, Kollias G, Vieth M, Hartmann A, Greten FR, Neurath MF, Neufert C. 2019, "STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis.", Gut. , 2019 Nov 4. pii: gutjnl-2019-319200. doi: 10.1136/gutjnl-2019-319200. [Epub ahead of print] [PubMed].

Roussou IG, Papanikolopoulou K, Savakis C, Skoulakis EMC. 2019, "Drosophila Bruton's Tyrosine Kinase Regulates Habituation Latency and Facilitation in Distinct Mushroom Body Neurons.", J Neurosci., 2019 Oct 30; 39(44):8730-8743 [PubMed].

Kaffe E, Magkrioti C, Aidinis V. 2019, "Deregulated Lysophosphatidic Acid Metabolism and Signalling in Liver Cancer", Cancers, 2019 Oct 23; 11(11). pii: E1626 [PubMed].

Tzouvelekis A, Eickelberg O, Kaminski N, Bouros D, Aidinis V. 2019, "Pulmonary Fibrosis", Frontiers Media SA. [Google Books].

Delivoria DC, Chia S, Habchi J, Perni M, Matis I, Papaevgeniou N, Reczko M, Chondrogianni N, Dobson CM, Vendruscolo M, Skretas G. 2019, "Bacterial production and direct functional screening of expanded molecular libraries for discovering inhibitors of protein aggregation", Scientific Advances, Oct 16; 5(10):eaax5108 [PubMed].

Patsalos A, Tzerpos P, Halasz L, Nagy G, Pap A, Giannakis N, Lyroni K, Koliaraki V, Pintye E, Dezso B, Kollias G, Spilianakis CG, Nagy L. 2019, "The BACH1-HMOX1 Regulatory Axis Is Indispensable for Proper Macrophage Subtype Specification and Skeletal Muscle Regeneration.", J Immunol. , 2019 Sep 15; 203(6):1532-1547. doi: 10.4049/jimmunol.1900553. Epub 2019 Aug 12. [PubMed].

Xylourgidis N, Min K, Ahangari F, Yu G, Herazo-Maya JD, Karampitsakos T, Aidinis V, Binzenhöfer L, Bennett AM, Kaminski N, Tzouvelekis A. 2019, "Role of Mitogen activated-kinase (MAPK)-phosphatase (MKP)-5 in pulmonary fibrosis", Am J Physiol Lung Cell Mol Physiol, 2019 Sep 4 [PubMed].

Katerina Papanikolopoulou, Jean Gouzi, Ilianna Roussou, Martina Samiotaki and Efthimios Skoulakis 2019, "Drosophila Tau negatively regulates translation and olfactory Long-Term Memory, but facilitates footshock habituation and cytoskeletal homeostasis", Journal of Neuroscience. , 39, 8315-8329 [PubMed].

Magkrioti C, Galaris A, Kanellopoulou P, Stylianaki EA, Kaffe E, Aidinis V. 2019, "Autotaxin and chronic inflammatory diseases", J Autoimmun., 2019 Aug 27: 102327 [PubMed].

Sberro H, Fremin BJ, Zlitni S, Edfors F, Greenfield N, Snyder MP, Pavlopoulos GA, Kyrpides NC, Bhatt AS. 2019, "Large-Scale Analyses of Human Microbiomes Reveal Thousands of Small, Novel Genes.", Cell. , 2019 Aug 6. pii: S0092-8674(19)30781-0. doi: 10.1016/j.cell.2019.07.016. [Epub ahead of print] [PubMed].

Spella M, Lilis I, Pepe MA, Chen Y, Armaka M, Lamort AS, Zazara DE, Roumelioti F, Vreka M, Kanellakis NI, Wagner DE, Giannou AD, Armenis V, Arendt KA, Klotz LV, Toumpanakis D, Karavana V, Zakynthinos SG, Giopanou I, Marazioti A, Aidinis V, Sotillo R, Stathopoulos GT. 2019, "Club cells form lung adenocarcinomas and maintain the alveoli of adult mice", Elife., 2019 May 29. ;8 [PubMed].

Polykratis A, Martens A, Eren RO, Shirasaki Y, Yamagishi M, Yamaguchi Y, Uemura S, Miura M, Holzmann B, Kollias G, Armaka M, van Loo G, Pasparakis M. 2019, "A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain.", Nat Cell Biol. , 2019 May 13. doi: 10.1038/s41556-019-0324-3. [Epub ahead of print] [PubMed].

Tzortzopoulos A, Thomaidou D, Gaitanou M, Matsas R, Skoulakis E. 2019, "Expression of Mammalian BM88/CEND1 in Drosophila Affects Nervous System Development by Interfering with Precursor Cell Formation", Neurosci Bull., 2019 May 11. doi: 10.1007/s12264-019-00386-5. [Epub ahead of print] [PubMed].

Karagianni N, Kranidioti K, Fikas N, Tsochatzidou M, Chouvardas P, Denis MC, Kollias G, Nikolaou C. 2019, "An integrative transcriptome analysis framework for drug efficacy and similarity reveals drug-specific signatures of anti-TNF treatment in a mouse model of inflammatory polyarthritis.", PLoS Comput Biol. , 2019 May 9; 15(5):e1006933. doi: 10.1371/journal.pcbi.1006933. eCollection 2019 May. [PubMed].

Matralis AN, Afantitis A, Aidinis V. 2019, "Development and therapeutic potential of autotaxin small molecule inhibitors: From bench to advanced clinical trials", Med Res Rev., 2019 May; 39(3):976-1013 [PubMed].

Krishna-Subramanian S, Singer S, Armaka M, Banales JM, Holzer K, Schirmacher P, Walczak H, Kollias G, Pasparakis M, Kondylis V. 2019, "RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury", Cell Death Differ. , 2019 Apr 15. doi: 10.1038/s41418-019-0330-9. [Epub ahead of print] [PubMed].

Tzilas V, Bouros E, Barbayianni I, Karampitsakos T, Kourtidou S, Ntassiou M, Ninou I, Aidinis V, Bouros D, Tzouvelekis A. 2019, "Vitamin D prevents experimental lung fibrosis and predicts survival in patients with idiopathic pulmonary fibrosis", Pulm Pharmacol Ther, 2019 Apr; 55:17-24. [PubMed].

Kerdidani D, Chouvardas P, Arjo AR, Giopanou I, Ntaliarda G, Guo YA, Tsikitis M, Kazamias G, Potaris K, Stathopoulos GT, Zakynthinos S, Kalomenidis I, Soumelis V, Kollias G, Tsoumakidou M. 2019, "Wnt1 silences chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma.", Nat Commun., 2019 Mar 29; 10(1):1405. [PubMed].

Scheibe K, Kersten C, Schmied A, Vieth M, Primbs T, Carlé B, Knieling F, Claussen J, Klimowicz AC, Zheng J, Baum P, Meyer S, Schürmann S, Friedrich O, Waldner MJ, Rath T, Wirtz S, Kollias G, Ekici AB, Atreya R, Raymond EL, Mbow ML, Neurath MF, Neufert C. 2019, "Inhibiting Interleukin 36 Receptor Signaling Reduces Fibrosis in Mice With Chronic Intestinal Inflammation", Gastroenterology, 2019 Mar; 156(4):1082-1097.e11. doi: 10.1053/j.gastro.2018.11.029. Epub 2018 Nov 16. [PubMed].

Bonetti NR, Diaz-Cañestro C, Liberale L, Crucet M, Akhmedov A, Merlini M, Reiner MF, Gobbato S, Stivala S, Kollias G, Ruschitzka F, Lüscher TF, Beer JH, Camici GG. 2019, "Tumour Necrosis Factor-α Inhibition Improves Stroke Outcome in a Mouse Model of Rheumatoid Arthritis.", Sci Rep. , 2019 Feb 18; 9(1):2173. doi: 10.1038/s41598-019-38670-z. [PubMed].

Papanikolopoulou K, Mudher A, Skoulakis E. 2019, "An assessment of the translational relevance of Drosophila in drug discovery.", Expert Opin Drug Discov, 2019 Jan 21: 1-11. doi: 10.1080/17460441.2019.1569624. [Epub ahead of print] [PubMed].

Koliaraki V, Chalkidi N, Henriques A, Tzaferis C, Polykratis A, Waisman A, Muller W, Hackam DJ, Pasparakis M, Kollias G. 2019, "Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis.", Cell Rep., 2019 Jan 15; 26(3):536-545.e4. doi: 10.1016/j.celrep.2018.12.072 [PubMed].