BSRC "Alexander Fleming" Publications

2014 - (35)

Kosmidis S, Missirlis F, Botella JA, Schneuwly S, Rouault TA, Skoulakis EM. 2014, "Behavioral decline and premature lethality upon pan-neuronal ferritin overexpression in Drosophila infected with a virulent form of Wolbachia.", Front Pharmacol. , 2014 Apr 4; 5:66. doi: 10.3389/fphar.2014.00066. eCollection 2014 [PubMed].

Papadopoulou A, Gole E, Moutafi A, Sfikas C, Oehrl W, Samiotaki M, Papadimitriou A, Papaevagelou V, Nicolaidou P. 2014, "Calcium sensing receptor in pregnancies complicated by gestational diabetes mellitus.", Placenta, 2014 Aug; 35(8):632-8. doi: 10.1016/j.placenta.2014.05.001. Epub 2014 Jun 2. [PubMed].

Rinotas V, Niti A, Dacquin R, Bonnet N, Stolina M, Han CY, Kostenuik P, Jurdic P, Ferrari S, Douni E. 2014, "Novel genetic models of osteoporosis by overexpression of human RANKL in transgenic mice", J Bone Miner Res. , 29(5) :1158-69 [PubMed].

Ioakeimidis F, Ott C, Kozjak-Pavlovic V, Violitzi F, Rinotas V, Makrinou E, Eliopoulos E, Fasseas C, Kollias G, Douni E. 2014, "A splicing mutation in the novel mitochondrial protein DNAJC11 causes motor neuron pathology associated with cristae disorganization, and lymphoid abnormalities in mice", PLoS One. , 2014 Aug 11; 9(8):e104237 [PubMed].

Perperopoulou FD, Tsoungas PG, Thireou TN, Rinotas VE, Douni E, Eliopoulos EE, Labrou NE, Clonis YD. 2014, "2,2'-Dihydroxybenzophenones and their carbonyl N-analogues as inhibitor scaffolds for MDR-involved human glutathione transferase isoenzyme A1-1", Bioorg Med Chem. , 22(15): 3957-70 [PubMed].

Alexiou P, Papakyriakou A, Ntougkos E, Papaneophytou CP, Liepouri F, Mettou A, Katsoulis I, Maranti A, Tsiliouka K, Strongilos A, Chaitidou S, Douni E, Kontopidis G, Kollias G, Couladouros E, Eliopoulos E. 2014, "Rationally Designed Less Toxic SPD-304 Analogs and Preliminary Evaluation of Their TNF Inhibitory Effects", Arch Pharm (Weinheim), 347(11) :798-805 [PubMed].

Tavora B, Batista S, Alexopoulou AN, Kostourou V, Fernandez I, Robinson SD, Lees DM, Serrels B, Hodivala-Dilke K. 2014, "Generation of point-mutant FAK knockin mice", Genesis. , 2014 Nov;52(11) 907-15. doi: 10.1002/dvg.22823. Epub 2014 Sep 30. [PubMed].

Schuijers J, Mokry M, Hatzis P, Cuppen E, Clevers H. 2014, "Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF.", EMBO J. , 2014 Jan 13;33(2): 146-56. doi: 10.1002/embj.201385358. Epub 2014 Jan 10. [PubMed].

Camps C, Saini HK, Mole DR, Choudhry H, Reczko M, Guerra-Assuncao JA, Tian YM, Buffa FM, Harris AL, Hatzigeorgiou AG, Enright AJ, Ragoussis J . 2014, "Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia", Molecular cancer, 13: 28. [PubMed].

Choudhry H, Schodel J, Oikonomopoulos S, Camps C, Grampp S, Harris AL, Ratcliffe PJ Ragoussis J,* Mole DR*. 2014, "Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2", EMBO reports , 15(1): 70-76 *senior co-authors [PubMed].

Radovich M, Ragoussis J. 2014, "Methods of quantifying microRNAs for hypoxia research: classic and next generation", Antioxidants & redox signaling, 21(8): 1239-1248 [PubMed].

Sagri E, Reczko M, Gregoriou ME, Tsoumani KT, Zygouridis NE, Salpea KD, Zalom FG Ragoussis J, Mathiopoulos KD. 2014, "Olive fly transcriptomics analysis implicates energy metabolism genes in spinosad resistance", BMC genomics, 15: 714 [PubMed].

Sagri E, Reczko M, Tsoumani KT, Gregoriou ME, Harokopos V, Mavridou AM, Tastsoglou S, Athanasiadis K, Ragoussis J, Mathiopoulos KD. 2014, "The molecular biology of the olive fly comes of age", BMC genetics, 15 Suppl 2: S8 [PubMed].

Choudhry H, Albukhari A, Morotti M, Hider S, Moralli D, Smythies J, Schodel J, Green CM, Camps C, Buffa F, Ratcliffe P, Ragoussis J**, Harris AL*, Mole DR* 2014, "Tumor hypoxia induces nuclear paraspeckle formation through HIF-2alpha dependent transcriptional activation of NEAT1 leading to cancer cell survival", Oncogene, [Epub ahead of print] *senior co-author [PubMed].

Roulis M, Nikolaou C, Kotsaki E, Kaffe E, Karagianni N, Koliaraki V, Salpea K, Ragoussis J, Aidinis V, Martini E, Becker C, Herschman HR, Vetrano S, Danese S, Kollias G. 2014, "Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis", Proc Natl Acad Sci U S A. , 2014 Oct 28; 111(43):E4658-67. doi: 10.1073/pnas.1415762111. Epub 2014 Oct 14. [PubMed].

Karagianni P, Talianidis I. 2014, "Transcription factor networks regulating hepatic fatty acid metabolism", Biochim Biophys Acta, doi: 10.1016/j.bbalip.2014.05.001. [PubMed].

Lezina L., Aksenova V., Ivanova T., Antonov VA., Tentler D, Fedorova O., Garabadgiu VA., Talianidis I , Melino G., Barlev NA. 2014, "KMTase Set7/9 is a critical regulator of E2F1 activity upon genotoxic stress", Cell Death Differ., 21:1889-1899 [PubMed].

Schmitt BM, Rudolph KL, Karagianni P, Fonseca NA, White RJ, Talianidis I, Odom DT, Marioni JC, Kutter C. 2014, "High-resolution mapping of transcriptional dynamics across tissue development reveals a stable mRNA-tRNA interface", Genome Res.25122613, 24:1797-1807. [PubMed].

Sarris M, Nikolaou K, Talianidis I . 2014, "Context-specific regulation of cancer epigenomes by histone and transcription factor methylation.", Oncogene. , 33:1207-1217 , [PubMed].

Duteil D., Metzger E., Willmann D., Karagianni P., Friedrichs N., Greschik H., Günther T., Buettner R. Talianidis I, Metzger D., Schüle R. 2014, "LSD1 promotes oxidative metabolism of white adipose tissue", Nature Comm. , 5:4093 [PubMed].

Skliris A, Papadaki O, Kafasla P, Karakasiliotis I, Hazapis O, Reczko M, Grammenoudi S, Bauer J, Kontoyiannis DL. 2014, "Neuroprotection requires the functions of the RNA-binding protein HuR", Cell Death Differ, 2014 Oct 10. doi: 10.1038/cdd.2014.158. [Epub ahead of print] [PubMed].

Nikolaidis C, Bouros E, Tzouvelekis A, Drakopanagiotakis F, Ntolios P, Kaltsas K, Boglou P, Anevlavis S, Steiropoulos P, Lambropoulou M, Mikroulis D, Kolios G, Aidinis V, Bouros D. 2014, "A biobank for Interstitial Lung Diseases according to the European Network EurIPF and ΒΒΜRI", Pneumon, vol 27(3) 209-213. [PDF].

Kotsinas A, Papanagnou P, Evangelou K, Trigas GC, Kostourou V, Townsend P, Gorgoulis VG. 2014, "ARF: a versatile DNA damage response ally at the crossroads of development and tumorigenesis.", Front Genet. , 2014 Jul 22; 5:236. doi: 10.3389/fgene.2014.00236. eCollection 2014. [PubMed].

Kostourou V, Papalazarou V. 2014, "Non-collagenous ECM proteins in blood vessel morphogenesis and cancer.", Biochim Biophys Acta. , 2014 Aug; 1840(8):2403-13. doi: 10.1016/j.bbagen.2014.02.018. Epub 2014 Feb 24. [PubMed].

Liu L, Christodoulou-Vafeiadou E, Rao JN, Zou T, Xiao L, Kyoung Chung H, Yang H, Gorospe M, Kontoyiannis D , Wang JY. 2014, "RNA-binding protein HuR promotes growth of small intestinal mucosa by activating the Wnt signaling pathway.", Mol Biol Cell. , 2014 Aug 27. pii: mbc.E14-03-0853. [Epub ahead of print] [PubMed].

Kraushar ML, Thompson K, Wijeratne HR, Viljetic B, Sakers K, Marson JW, Kontoyiannis DL , Buyske S, Hart RP, Rasin MR. 2014, "Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R.", Proc Natl Acad Sci U S A. , 2014 Aug 25. pii: 201408305. [Epub ahead of print] [PubMed].

Turin L, Skoulakis EM, Horsfield AP. 2014, "Electron spin changes during general anesthesia in Drosophila.", Proc Natl Acad Sci U S A. , 2014 Aug 26; 111(34):E3524-33. doi: 10.1073/pnas.1404387111. Epub 2014 Aug 11. [PubMed].

Ehlken H, Krishna-Subramanian S, Ochoa-Callejero L, Kondylis V, Nadi NE, Straub BK, Schirmacher P, Walczak H, Kollias G, Pasparakis M 2014, "Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout", Cell Death Differ, 2014 Jun 27. doi: 10.1038/cdd.2014.83. [Epub ahead of print] [PubMed].

Hemmerling J, Heller K, Hörmannsperger G, Bazanella M, Clavel T, Kollias G, Haller D 2014, "Fetal exposure to maternal inflammation does not affect postnatal development of genetically-driven ileitis and colitis", PLoS One., 2014 May 21; 9(5):e98237. [PubMed].

Fan AX, Papadopoulos GL, Hossain MA, Lin IJ, Hu J, Tang TM, Kilberg MS, Renne R, Strouboulis J, Bungert J. 2014, "Genomic and proteomic analysis of transcription factor TFII-I reveals insight into the response to cellular stress", Nucleic Acids Res. , 2014 May 29. pii: gku467 [Epub ahead of print] [PubMed].

Kafasla P, Skliris A, Kontoyiannis DL. 2014, "Post-transcriptional coordination of immunological responses by RNA-binding proteins.", Nat Immunol., 2014 May 19; 15(6):492-502. doi: 10.1038/ni.2884. [PubMed].

Leppkes M, Roulis M, Neurath MF, Kollias G ,Becker C. 2014, "The pleiotropic functions of TNF-α in the regulation of the intestinal epithelial response to inflammation", Int Immunol. , 2014 May 12 [Epub ahead of print] [PubMed].

Shi L, Sierant MC, Gurdziel K, Zhu F, Cui S, Kolodziej KE, Strouboulis J, Guan Y, Tanabe O, Lim KC, Engel JD 2014, "Biased, Non-equivalent Gene-Proximal and -Distal Binding Motifs of Orphan Nuclear Receptor TR4 in Primary Human Erythroid Cells.", PLoS Genet. , 2014 May 8; 10(5):e1004339. [PubMed].

Kosmidis S, Missirlis F, Botella JA, Schneuwly S, Rouault TA, Skoulakis EM. 2014, "Behavioral decline and premature lethality upon pan-neuronal ferritin overexpression in Drosophila infected with a virulent form of Wolbachia.", Front Pharmacol, 2014 Apr 4;5:66. doi: 10.3389/fphar.2014.00066. eCollection 2014 [PubMed].

Sriskantharajah S, Gückel E, Tsakiri N, Kierdorf K, Brender C, Ben-Addi A, Veldhoen M, Tsichlis PN, Stockinger B, O'Garra A, Prinz M, Kollias G ,Ley SC. 2014, "Regulation of Experimental Autoimmune Encephalomyelitis by TPL-2 Kinase", J Immunol. , 2014 Mar 17. [Epub ahead of print] [PubMed].